Miracle HOT or COLD box – an all round saving on energy

Miracle Hot Box



The Miracle Hot Box – A powerless slow cooker that pays for itself. Does it really work?

The short answer is YES. And fantastically well at that.

Ok, I know what you are thinking. This is a fabric box, how can it possibly cook food? That’s what I thought the first time I used mine. I was dubious but decided to give it a whirl anyway. I made chicken soup by throwing everything into the pot like I normally do – a whole chicken, vegetables and enough water to cover, heated it up well, stirred hopefully and stuck it in the box. I nearly burnt my hand when I tried to grab the pot handle some 8 hours later! Everything was hot, cooked and delicious. My, oh my, I was gobsmacked.


The Secret

The Miracle Hot Box is a new twist on a very old idea – powerless cooking through heat retention. Once you have brought food to a rolling boil (15 minutes or less) you quickly put the lid on, tuck the pot into the Miracle Hot Box and go on about your business. Food continues to cook, gently but thoroughly without further intervention – from you in the way of stirring or checking and from a power source of any kind. The Hot Box is so well insulated that the temperature drops very slowly and the food cooks evenly – preserving taste, texture and vitamins. To get the most out of your Miracle Hot Box, use these simple tips and tricks.


Save Time, Money and More

This kind of cooking means that not only do you save money, but you save time, stress and nutrients to boot. You can’t burn, dry out or overdo anything and you won’t end up burning the house down either! You can safely leave food to cook away all night while you sleep or at home when you are at work and even in the car while you drive to that picnic. Imagine setting off on a camping holiday with your dinner cooking in the Miracle Hot Box on the way there. All you have to do is set up camp and dish up.

The best thing about the Miracle Hot Box is that the food is ready to eat when you are. Even if it’s done to perfection after 2 or 3 hours, it stays hot for ages without spoiling, dehydrating or overcooking. How’s that for fuss-free cooking?

Good for soups, stews, porridge, mealy meal, casseroles, rice, pot roasts and bread, the Miracle Hot Box is also perfect for cheaper but tasty cuts of meat like brisket that require longer, slower cooking. Did I hear you say “savings”?

A Miracle Cooler as well

The Miracle Hot Box even doubles up as a cooler to keep frozen goods frozen. It is as light as a feather so you can take it in the car when you go shopping. It’s also useful as a pillow.

So if you are time deprived, too busy to fret over a hot stove, interested in healthy cooking, a lazy or a reluctant cook, wanting to save money, care about your carbon foot print, need a back-up plan for emergencies like power outages or all of the above – the Miracle Hot Box is for you. It will revolutionise your life.



This fabulous product is available in South Africa via these links at a very reasonable price :

 If you want to find out more about this amazing energy saving cooker, give us a call on 072 419 2340 or e mail hotbox@miraclewater.co.za



Gardening for depression

Antidepressant Microbes In Soil:

How Earth Makes You Happy


Image by amoceptum

By Bonnie L. Grant

Prozac may not be the only way to get rid of your serious blues. Soil microbes have been found to have similar effects on the brain and are without side effects and chemical dependency potentials. Learn how to harness the natural antidepressant in soil and make yourself happier and healthier. Read on to see how dirt makes you happy.

Natural remedies have been around for untold centuries. These natural remedies included cures for almost any physical ailment as well as mental and emotional afflictions. Ancient healers may not have known why something worked but simply that it did. Modern scientists have unraveled the why of many medicinal plants and practices but only recently are they finding remedies that were previously unknown and, yet, still a part of the natural life cycle. Soil microbes and human health now have a positive link which has been studied and found to be verifiable.

Soil Microbes and Human Health

Did you know that there’s a natural antidepressant in soil? It’s true. Mycobacterium vaccae is the substance under study and has, indeed, been found to mirror the effect on neurons that drugs like Prozac provide. The bacterium is found in soil and may stimulate serotonin production, which makes you relaxed and happier. Studies were conducted on cancer patients and they reported a better quality of life and less stress.

Serotonin has been linked to such problems as depression, anxiety, obsessive compulsive disorder and bipolar problems. The bacterium appears to be a natural antidepressant in soil and has no adverse health effects. These antidepressant microbes in soil may be as easy to use as just playing in the dirt.

Most avid gardeners will tell you that their landscape is their “happy place” and the actual physical act of gardening is a stress reducer and mood lifter. The fact that there is some science behind it adds additional credibility to these garden addicts’ claims. The presence of a soil bacteria antidepressant is not a surprise to many of us who have experienced the phenomenon ourselves. Backing it up with science is fascinating, but not shocking, to the happy gardener.

Mycrobacterium antidepressant microbes in soil are also being investigated for improving cognitive function, Crohn’s disease and even rheumatoid arthritis.

How Soil Makes You Happy

Antidepressant microbes in soil cause cytokine levels to rise, which results in the production of higher levels of serotonin. The bacterium was tested both by injection and ingestion on rats and the results were increased cognitive ability, lower stress and better concentration to tasks than a control group.

Gardeners inhale the bacteria, have topical contact with it and get it into their bloodstreams when there is a cut or other pathway for infection. The natural effects of the soil bacteria antidepressant can be felt for up to 3 weeks if the experiments with rats are any indication. So get out and play in the dirt and improve your mood and your life.

“Identification of an Immune-Responsive Mesolimbocortical Serotonergic System: Potential Role in Regulation of Emotional Behavior,” by Christopher Lowry et al., published online on March 28, 2007 in Neuroscience.
http://extension.oregonstate.edu/lane/sites/default/files/images/gg607.pdf (pg 12)
Mind & Brain/Depression and Happiness – Raw Data “Is Dirt the New Prozac?” by Josie Glausiusz, Discover Magazine, July 2007 Issue. http://discovermagazine.com/2007/jul/raw-data-is-dirt-the-new-prozac

This article was last updated on 08/12/14


World’s Oldest Antibiotic Also Shows Promise as anti-cancer therapy

World’s Oldest Antibiotic Also Shows Promise as an Anti-Cancer Therapy



Colloidal silver is a powerful healer, despite irrational FDA opposition to it.

Silver has been used medicinally throughout the ages, with great success. And now some very promising research is being done on silver as a cancer treatment. Patients have previously been treated with chemotherapy drugs containing another metal, platinum. In a head-to-head comparison against a leading platinum-based chemo drug, cisplatin, a silver-based drug was found to be just as effective—and far less toxic to normal cells than platinum. Dr. Charlotte Willans, the lead researcher, calls the research an important step in the quest for effective, non-toxic cancer treatments.

Silver also happens to be the world’s oldest known antibiotic. There’s written evidence that the ancient Egyptians made use of it; the ancient Greeks and Romans stored their water, wine, and other liquids in silver vessels to prevent spoiling and contamination; ancient Chinese emperors ate with silver chopsticks, and wealthy Europeans in the Middle Ages used silver utensils to protect themselves from illness (we still call our eating utensils “silverware” despite it being made from other metals these days).

In the 1800s and early 1900s, colloidal silver compounds were widely used to fight infections, though silver fell out of favor in the 1930s with the development of the first modern antibiotics. Even so, silver is still popularly used today to treat water, purify air, and is used in medical dressings prevent infection in burn victims. Very importantly in today’s world, germs cannot develop a resistance to silver.

The big problem with antibiotic drugs, we now know, is that bacteria can become resistant to them, adapting into “superbugs” that are very difficult to treat. The problem, as we noted in January, is exacerbated by overuse of antibiotics—particularly in animals raised for food, where 80% of US antibiotics are used.

Despite the long history of successful silver usage, including its current use in wound dressings and burn salves, the FDA’s official position is that silver is “not safe or effective for treating any disease or condition.” A 1996 FDA rule declared all over-the-counter silver products to be unsafe and “misbranded.”

The government and other skeptics often claim that colloidal silver can cause argyria—a condition in which the skin turns bluish gray. However, argyria has only been found to occur in response to prolonged exposure to or ingestion of silver compounds, especially silversalts, which are not present in true colloidal silver but are found in cheap imitations.

This was demonstrated rather dramatically in 2008 by Paul Karason, the fellow whom the news media dubbed the “Blue Man.” Although the news media continually reported that he was taking colloidal silver, interviews with Mr. Karason indicated that was apparently making his own silver compounds at home and ended up making silver chloride—a silver salt—which he both consumed in excessive quantities and regularly smeared on his skin before using tanning beds! Silver salt compounds are great for making photographic paper—but not for taking internally or applying to the skin.

A study published earlier this year demonstrated that bacteria are now mutating to evade vaccines for childhood pneumonia and meningitis. So we not only have antibiotic-resistant superbugs, we have vaccine-resistant ones as well. This is just the latest indication that the “miracle drugs” and vaccines of the mid-to-late 1900s are not standing the test of time.

Contrast this with colloidal silver, which has been used as a bactericide for over a millennium—and has never produced silver-resistant bacteria! The recent research into silver as an anti-cancer agent is exactly the kind of research that today’s medical experts should be exploring—and would be, but for FDA opposition.

Why is the FDA so stubbornly opposed? Presumably because the agency does not like competition for its approved patented drugs which are derived from natural sources. People dying from resistant bugs does not seem to move the FDA—they’re only interested in new patented drugs that might quell the superbugs, even though such drugs are not being produced much, and even when they are, they often prove to be too toxic to use.

Kefir and diabetes

Kefir and diabetes

      • Kefir
      • Kombucha


Captain of your ship and the master of your destiny.
Shaped by the light we let through us

I remember that day quite vividly. It was over ten years ago. It was February and bitter cold outside. I made myself  a breakfast that I thought was healthy. Fiber One cereal and skim milk. Thirty minutes later a terrible feeling came over me, one that I recognized from having gestational diabetes with the pregnancy of my daughter. I had a blood sugar meter that I could test my blood sugar with, and when I saw the numbers my heart sank. I picked up the phone to call my brother-in-law, who was a medical physician. He very gently and kindly confirmed for me what I already knew. My blood sugar was too high and out of the normal range. These were diabetic numbers, but I already knew this. Devastated, I walked into the kitchen where my family was, and  burst into tears.

Kefir with Peaches

How could I have gone from running five miles a day and racing through life to having diabetes and high blood pressure? And then watching my family, one by one, deteriorate as well. It really broke me. I felt as though it was my fault and I could not find my way out of this situation. Having a four pound preemie who was delivered prematurely in an effort to save my life  just heaped more guilt upon me as I watched her struggle to grow and thrive. It was these experiences that changed my life. Changed everything, actually, and caused me to cry out from a deep place in my soul for help. Standing on the other side of these experiences, though, has caused me to be so thankful for the pain they caused.

A couple of months ago I was talking to my husband about these very incidences. Not only did I find the answers I was seeking, but I found more joy and understanding of our body and how it teaches us if we listen. Maybe It was because I can help others find answers with the things that have so effectively changed me. Many people ask for wellness, but I have discovered that you must tune yourself to look for the solution and not focus on the pain of what you are living. I used to tell myself that I would find the answer, that it would come to me. Then I would hang on to that answer and hope for dear life. The answers came swiftly and turned my life upside down.

The one thing I see most consistently in my classes is the lowering of blood sugar after people start drinking kefir every day. The emails I get are quite astounding, to say the least. In the beginning it was my story that made me realize how effective it was. Kefir had such an impact on me that it started me on a journey that has led me to a greater understanding of who I was and the profound effect that food can have on the body.

It was ten years ago when I discovered during my third pregnancy that I had gestational diabetes. I managed it quite successfully during my pregnancy. The diabetes went away only to return with a vengeance seven months later, with a slew of other problems. I knew a lot about diabetes. My youngest sister and niece had type 1 diabetes and my dad had type 2 diabetes. Watching my sister live with this from the time she was ten, and gaining understanding of what it can do to the body was a life-altering journey for me. I was not naïve about the difference between type 1 and 2 diabetes. They are quite different in nature – one is caused by the autoimmune system attacking itself (type 1) and the other (type 2) is caused by a condition known as “insulin resistance.” In fact, in the early stages of type 2 diabetes, there’s plenty of insulin around but the body can’t use it effectively. I had type 2 diabetes and knew It was not something to fool around with it. It can shorten your life and make you feel terrible.


When I started drinking kefir, I was shocked at how quickly it lowered my blood sugar and blood pressure. So I did experiments on myself to see if it really was the kefir. After many trials, I was convinced it was the kefir. Drinking at least a cup of kefir in a smoothie every day, I watched my numbers normalize and diabetes quickly became a thing of the past for me.
My friend and CPA was the one who really clued me in to how effective kefir was on blood sugar. She had just  been diagnosed with diabetes in the last few years and it had been caused by her life style choices and sedentary life style. We talked about this often. She really wasn’t wanting to change her eating habits very much despite the diagnosis. I had told her to try kefir and every time she did, it would lower her blood sugar quite dramatically. She never wanted to be bothered making it and would fall off the wagon over and over again. So, a couple of months ago she called me in a panic. Her blood sugars were so bad that they were going to put her on insulin shots. She didn’t do very well with making kefir every day so I told her to use the kefir packages and make a gallon at a time. Then she would always have some kefir and wouldn’t have to make it every day. You have to meet people where they are. Some people aren’t going to do the things that I am willing to do. I always try to find their path of least resistance and something they will actually do. The results were once again a lowering of her blood sugar so that she never did have to go on the shots. She still has diabetes, but it is well managed and under control. Her doctor was so impressed that she asked for a copy of my book.

So why does kefir lower blood sugar? It is still something that one day I plan to fully understand, but these are the bits and pieces I have discovered.

Normally, you have about 300 different strains of bacteria in your gut. About ten to twelve pounds of your body weight is this intestinal colony of bacteria. If you are healthy, most of this colony consists of healthy families of bacteria, but if you are unwell, trouble will ensue. In total, you are at least 100 trillion cells of bacteria. You and I are living sacks of bacteria and nobody is really talking about this. Bacteria outnumber the cells in your body. When things go haywire, you can be sure that your bacteria have gotten out of balance. Diabetes is very inflammatory. The blood is not moving through the arteries in a fluid fashion, but instead creeps through like sludge when blood sugar is high. Kefir is anti-inflammatory and this will help every function in the body. It is also full of enzymes, which relieve stress on the pancreas. It is full of beneficial bacteria that help cells communicate with one another in ways that only essential bacteria can communicate. Kefir is an important probiotic that has many bioactive ingredients, which give it unique health benefits. Consuming kefir helps a myriad of problems. It did for me and countless others I have helped.

It has been almost ten years and the diabetes has never returned. The difference between how I feel now and when I had diabetes is like comparing different people. I can feel with every fiber of my being that my body has found its rhythm and loves life. The body gives us clues every day and the better you feel, the more you will know that you are on the right path.

One of the reasons I have a blog, write books, and teach classes, is because I really do want others to feel the same wellness and joy I feel. When you feel better you do better. It just spills out of you.
Don’t be surprised if it happens to you, too. Joy is hard to control.

Wishing you all well. ~ Donna

How To Make Kefir

Making Kefir

Three foods that can change your life ~ The Trilogy

Three foods that can change your life ~

The Trilogy


is a set of three works of art that are connected, and that can be seen either as a single work or as three individual works.

The Trilogy

Fermentation is an art form and each individual cultured food is, in and of itself, unique. These three foods each provide different good bacteria and yeasts that enhance the trillions of bacteria in the body and allow them to thrive, grow, and multiply. This allows you, the host, the opportunity to heal disease, remove pathogens, enhance digestion, make serotonin, and experience a multitude of other opportunities for healing that otherwise would not have been possible. This is what I call ~ The Trilogy

The Trilogy is my secret weapon. It has changed my life and so many other lives. What is the trilogy? Three magic and powerful foods that I consume every day without fail. They are kefir, kombucha, and cultured vegetables; and they bring me more joy than I can express in words. This is the thing I noticed the most when I taught others about cultured foods – when they consumed one of these foods they would get better, but when they consumed all three they seemed to thrive! These three foods (kefir, kombucha, and cultured vegetables) are unique unto themselves and each food contains a different set of bacteria and yeasts that we need to thrive and feel alive.

Homemade kefir has 50 plus good bacteria and yeasts. It is so powerful that I recommend people consume only small amounts when they first start kefir, so as not to overwhelm their body with good bacteria. These bacteria are strong and will go to work killing pathogens and bad bacteria, making some individuals uncomfortable. You can read more about that on this blog post: The Healing Crisis.

Kefir and Raspberries

Kefir and its special bacteria microbes will make you its home and keep things in balance for you. It will add probiotics to any kind of milk, whether it be cow, goat, coconut, or almond milk. It will transform the milk, increasing vitamins and nutrient absorption, and it will do this sitting on your counter in a glass jar while you go about your day. Then when you consume it, you will find it will digest your food, reduce inflammation, make elimination a breeze, and, well, the list is so long it would take this entire page to explain it all. It transformed me and I don’t go a day without it. It was the first cultured food I started with and the one that changed me the most.

Kombucha with fruit

Kombucha..my, my, my, how I love this fermented tea. Talk about powerful! It is a wonder drink and there is nothing else like it on the market. It helps remove toxins through the kidney, liver, and bowels. You might notice, as I did, that kombucha can help you lose a lot of excess water weight.  It helps you eliminate the excess swelling and fluid that accumulates in your tissues from chemically laden foods and alcohol. I was talking with a friend this weekend and he noticed the same thing. On the weekends, he tends to drink a lot of alcohol, doesn’t have his kombucha, and will retain a lot of fluids. The body tends to do this when it has a lot of toxins. On weekdays when he goes back to drinking his kombucha, he will release the water weight and easily lose five pounds. This does not surprise me because kombucha is a liver cleanser and it will assist your liver in removing toxins that have accumulated. Kombucha will also help relieve the water retention that often happens when the body protects the organs by holding on to water when under stress or a heavy toxic load.

Summer Kraut

Cultured Vegetables: Everybody knows that vegetables are so, so good for you – but when you ferment vegetables, they become more powerful than they were previously. Let me tell you my little story about these veggies. I went on a trip and didn’t have my cultured veggies for two weeks. I ate everything imaginable under the sun and enjoyed it all. Delicacies and desserts and, well, I was having a good time but having very little, if any, cultured foods. My body has become accustomed to these foods and without them I am fine for a while; but after a week or two, it revolts. I think it actually gets mad at me and will create symptoms to get my attention. I will get red rashes on my fingers and body odor occurs which I don’t have often since this is caused by bad bacteria. My stomach will start to feel bloated and, well… lets just say that elimination is not as pleasant as it can be. But the worst thing of all is that I get grouchy and cranky. Yeah, my family makes sure that I eat my cultured foods. But as soon as I have as little as a large spoonful of cultured vegetables, my insides do a happy dance and the cultured vegetables start working inside of me. Believe you me, in a day or two I can feel it, see it, smell it, and know it. They will clean me out, and then some. Talk about housecleaning! They go at it, removing all the inappropriate food debris I had been eating and making me feel great again.

The Trilogy DVD
So this is the Trilogykefirkombucha, and

Rediscover a natural, inexpensive cancer treatment agent mostly forgotten or ignored

Rediscover a natural, inexpensive cancer treatment agent mostly forgotten or ignored            

DMSO (dimethyl sulfoxide)


Thursday, August 07, 2014 by: Paul Fassa

(NaturalNews) You may remember the stir that DMSO created in the 1970s when it emerged as a miraculous healing agent and adjuvant for treating many health issues. Some MDs were using it on cancer patients successfully. Then, DMSO mostly faded out of the natural healing picture.

Recently, the Camelot Cancer Care clinic in Tulsa, Oklahoma, featured DMSO as a major part of their protocol, but it was shut down in 2013 by the FDA and FBI after producing a very high healing rate among cancer patients. Apparently, they’ve reopened with the stipulation that they would no longer use laetrile, a natural extract banned in the USA but used effectively elsewhere.

A major aspect of Camelot’s currently allowable orthomolecular (mega-dose vitamin) treatment incorporates DMSO. It has been proven to carry healing compounds deeply and rapidly into tissue while also having its own properties that promote cancer cell apoptosis (cell death). [1]

Most normal cells are programmed for apoptosis as part of their cycle for allowing new cells to generate. Cancer cells don’t have this property. So they claim immortality by never dying on their own and stick around to form tumors.

DMSO (dimethyl sulfoxide): From industrial solvent to cancer solvent

Medical interest surfaced in the early 1960s at the Oregon Health and Science University Medical School, where Dr. Stanley Jacob discovered that DMSO could penetrate skin and organ membranes without damaging them. Dr. Jacob researched DMSO further and found several topical analgesic applications for animals and humans.

He went further with injecting or ingesting DMSO for a bladder malady, interstitial cystitis (IC). In 1978, the FDA allowed DMSO to be used for IC. Dr. Jacob has consumed a teaspoonful of DMSO daily for over 30 years and has claimed perfect health. [2]

DMSO has been used to alleviate Crohn’s disease suffering. You can search on YouTube for “DMSO 60 Minutes” videos and witness interesting interviews with Dr. Jacob and some of his patients treated for assorted ailments. https://www.youtube.com/watch?v=u0i7jARfKeI&list=PL557FE6FD0033B580

But the big deal with DMSO involves treating cancer. R. Webster Kehr of Cancer Tutor and other sites reported on a series of experiments with cancerous animals which discovered that DMSO targets cancer cells while leaving healthy cells alone. Kehr recommends using DMSO to get high-pH cesium more deeply into tissues contaminated with cancer cells. [3]

There have been oncologists who have used DMSO with some existing chemotherapy drugs effectively. Instead of the chemo destroying everything in its path as usual, the DMSO escorted the chemo to cancer cells only, thus greatly reducing the amount of chemotherapy needed for a result.

Maybe that’s why doctors who had used FDA/AMA-approved chemo drugs with DMSO were shut down. Using only 10% of any chemotherapy drug and getting positive results negatively affects Big Pharma and oncologists’ profits.

However, DMSO has been used by itself successfully for cancer. There have been anecdotal cures, and a scientific study published in 2010 in India mentions that much in vitro (lab culture) testing has demonstrated DMSO’s ability to induce apoptosis in cancer cells. [4]

They went beyond test tubes and cultures by using DMSO on live animals with non-Hodgkins lymphoma, a blood cancer disease. The DMSO induced cancer cell apoptosis with tumor reduction while leaving non-cancerous cells unharmed (http://www.ncbi.nlm.nih.gov).

The FDA requires DMSO be sold as a “solvent” even if it’s pure. That’s what the label is supposed to read to avoid FDA issues. You can order directly from Dr. Jacob’s site or Amazon. And you can get a better understanding of DMSO for cancer by visiting the Camelot website from the sources below.

Sources for this article include:

[1] http://www.camelotcancercare.com

[2] http://www.dmso.org

[3] http://www.cancertutor.com

[4] http://www.ncbi.nlm.nih.gov



About the author:
Paul Fassa is dedicated to warning others about the current corruption of food and medicine and guiding them towards direction for better health with no restrictions on health freedom.
Learn more: http://www.naturalnews.com/046356_DMSO_cancer_treatment_cell_apoptosis.html#ixzz3D2KlVW00

Colloidal Silver clinical studies and reports


Clinical Studies and Reports on the
Antimicrobial Qualities of Colloidal Silver








The following PDF documents consist of a variety of clinical studies and independent research reports on the antimicrobial qualities of colloidal silver-related products including silver ions, silver compounds, silver nanoparticles, nanosilver compounds, silver-impregnated and silver-coated products, and many other forms of silver being used in a wide variety of ways, but almost all for the purpose of benefitting from the powerful antimicrobial qualities of silver itself.

These studies and reports are supplied for informational purposes only, and should not be construed in any way as providing medical advice or guidance. They cover a wide range of data on silver, including some surprising findings and discoveries regarding silver’s powerful antimicrobial, infection-fighting and disinfectant qualities.

These studies and reports are compiled here with the intent of giving the reader or researcher a general understanding of the many uses of antimicrobial silver, from a variety of viewpoints, both clinical and personal. The studies are not meant to convey efficacy of any particular colloidal silver product.

Because research into antimicrobial silver is ongoing, and because opinions and conclusions tend to vary depending upon the factors involved in different studies, these studies and reports should be considered merely as a starting point for your own research, and not be considered the final word on silver and its many antimicrobial, infection-fighting or disinfectant benefits.

Note to Publishers and Authors: If you feel any of these PDF files are on this site in violation of copyright, please inform me immediately by email, at sales@TheSilverEdge.com, or at the phone number at the bottom of this page. These PDF files have been garnered from a variety of internet sources where they were found posted with no restrictions. They are here under fair use, and for non-commercial informational purposes only.

Note to Readers: The following files are PDF files. This means you need a program called Adobe Acrobat on your computer, in order to open and view them. Most computers come pre-installed with Adobe Acrobat. But yours may not. If that’s the case, you can download Adobe Acrobat at no cost fromhttp://get.adobe.com/reader. Readers should also take note that downloading, emailing, posting or any other re-publication of these files in other forums may constitute a violation of the author’s copyright.

120 Years of Nanosilver History Demonstrate Its Safety and Repudiate Attempts to Paint It As a “New Substance” With “Unknown Risks”
Nanosilver is assumed to be a new material because of the relatively recent emergence of the term “nano”. However, on close inspection nanosilver materials have a long, 120-year history of relatively safe and regulated use, chiefly in the form of colloidal silver. Historical perspective demonstrates that nanosilver has been intentionally manufactured and adopted commercially across a wide spectrum of everyday applications for many decades. To declare nanosilver materials as “new chemicals” with “unknown properties” that are “potentially harmful” simply on the basis of a change in nomenclature to the term “nano,” and ignoring the accumulated knowledge of its scientific and regulatory heritage demonstrating both safety and efficacy in a wide range of applications, would be a mistake that does not serve the public interest.
First Ever Double-Blind Human Ingestion Study on Nanosilver
American Biotech Labs has just released what is believed to be the first ever human ingestion safety study on a colloidal silver supplement. The published abstract for the study states that ingestion of the patented ABL nanosilver particle showed no negative effects on any tested system in the body. The study included 3, 7 and 14-day exposures to American Biotech Labs 10 ppm (15 ml/day) silver solution in a double-blind, placebo controlled cross-over phase design. Healthy volunteer subjects (36 subjects in all, 12 per each time-exposure studied), underwent complete metabolic, blood and platelet count, urinalysis tests, sputum hyper-responsiveness and inflammation evaluation, physical examinations, vital sign measurements, and magnetic resonance imaging of the chest and abdomen at baseline and at the end of each phase. According to the study authors, “No clinically important changes in any metabolic, hematologic, or urinalysis measure identified were determined. No morphological (or structural) changes were detected in the lungs, heart (cardiac function) or abdominal organs. No changes were noted in sputum reactive oxygen species or in pro-inflammatory cytokines.”
Ionic Silver Safety: An In Vitro Toxicity Study of a Colloid Silver Health Product and Atomic Quantum Clusters of Silver and Gold (Ionosil Study)
Is colloidal silver toxic to cells? In this in vitro clinical study conducted in June 2007 at The Faculty of Pharmaceutical Sciences, Copenhagen University, the researcher set out to discover if Ionosil (i.e., Sweden’s leading brand of ionic colloidal silver) is toxic to cells, using human alveolar lung epithelial cell line A549. The researcher compared the effects of Ionosil to atomic gold and silver quantum clusters on the cells, looking for cytotoxicity (i.e. cell damage), inflammation and DNA damage. No toxicity, DNA damage or inflammation was found from the ionic colloidal silver solution.
Nanoparticle Colloidal Silver Demonstrated Safe For Humans
This company got tired of the falsehoods and misconceptions being promulgated by against colloidal nanosilver by environmentalists, and has set the record straight!
Safety Information Related to Nanoscalar-Oligodynamic Silver Ions
Another company sets the record straight regarding the safety of nano-sized ionic colloidal silver!
An Evaluation of Acute Toxicity of Colloidal Silver Nanoparticles
Researchers tested mice for acute oral toxicity, eye irritation, corrosion and dermal toxicity of colloidal silver nanoparticles (AgNPs) following OECD guidelines. Oral administration of AgNPs at a limited dose of 5,000 mg/kg produced neither mortality nor acute toxic signs throughout the observation period. Percentage of body weight gain of the mice showed no significant difference between control and treatment groups. In the hematological analysis, there was no significant difference between mice treated with AgNPs and controls. Blood chemistry analysis also showed no differences in any of the parameter examined. There was neither any gross lesion nor histopathological change observed in various organs. The results indicated that the LD50 of colloidal AgNPs is greater than 5,000 mg/kg body weight. In acute eye irritation and corrosion study, no mortality and toxic signs were observed when various doses of colloidal AgNPs were instilled in guinea pig eyes during 72 hr observation period. However, the instillation of AgNPs at 5,000 ppm produced transient eye irritation during early 24 hr observation time. No any gross abnormality was noted in the skins of the guinea pigs exposed to various doses of colloidal AgNPs. In addition, no significant AgNPs exposure relating to dermal tissue changes was observed microscopically. In summary, these findings suggest that colloidal AgNPs could be relatively safe when administered to oral, eye and skin of the animal models for short periods of time.
Genotoxicity, Acute Oral and Dermal Toxicity, Eye and Dermal Irritation and Corrosion, and Skin Sensitization Evaluation of Silver Nanoparticles
This is an abstract of a 2012 study published in the journal Nanotoxicology, in which researchers tested silver nanoparticles for genotoxicity, acute oral and dermal toxicity, eye and dermal irritation and corrosion, and skin sensitization. In the bacterial and animal tests performed, the researchers found that silver nanoparticles, at fairly high dosage levels, do not induce genotoxicity or abnormal signs of mortality. There was no oral or dermal toxicity. There was no acute eye or dermal irritation of corrosion, and extremely low skin sensitization. Some cytotoxicity (cell toxicity) was observed in the bacterial tests, which is to be expected since silver is a known bacteriocide. One test animal out of 20 showed low level signs of erythema (i.e., superficial reddening of the skin), prompting researchers to classify the silver nanoparticles used as “a weak skin sensitizer.”
The Altman Study: Colloidal Silver, Where Does It Go When You Drink It? How Long Does It Stay There?
The classic 1990’s study demonstrating the body’s ability to effectively excrete silver.
Safety and Efficacy of Intravenous Oligodynamic Silver
Dr. Kent Holtorf, M.D. discusses historical safety and efficacy of various forms of colloidal silver, used orally and intravenously, including oligodynamic silver. [*Web editor's note: Never use colloidal silver intravenously except under a doctor's direction and supervision. Some deaths attributed to the use of intravenous colloidal silver have been recorded in early medical literature. Additionally, colloidal silver for intravenous use must be prepared as an isotonic solution to avoid the lysing of red blood cells.]
Silver Nanoparticles Interactions with the Immune System: Implications for Health and Disease
In this study overview of the way silver nanoparticles interact with the immune system, researchers found that silver nanoparticles strongly inhibited cytokine production, and did not show pro-inflammatory effects. According to the study authors, “It has been shown in vivo that silver NPs act to decrease inflammation through cytokine modulation.” The implication being that silver nanoparticles may one day play a key role in decreasing inflammation in inflammatory medical conditions. The study overview also found that topical application of silver nanoparticles promotes wound healing.
Evaluation of Hazard and Exposure Associated with Nanosilver and Other Nanometal Oxide Pesticide Products
The Silver Nanotechnology Working Group demonstrates the history and safety of commercial products containing silver nanoparticles.
Silver Nanoparticles: No Threat to the Environment
Dr. George J. Maass demolishes the idea that silver nanoparticles pose a threat to the environment.
Assessment of Nanosilver In Textiles On the Danish Market: No Likely Risk to Environment or Humans
In a six-month study (Sept. 2011 to March 2012) funded by the Danish Environmental Protection Agency, carried out by the Danish Technological Institute and published by the Danish Ministry of the Environment, it was found that nanosilver in textiles including various forms of clothing as well as cleaning cloths and children’s toys pose “no risk of health effects or environmental effects.” Indeed, regarding the potential for harm to the environment, the study authors unequivocally state, “…the scenario for environmental exposure through discharge of sewage effluent is not likely to pose a risk of biological effects in the aquatic environment arising from the use of nanosilver in textiles…” And regarding human exposure, the researchers further state, “The calculated risk ratios relevant for the three selected human exposure scenarios indicate that the risk from each individual scenario is very low. Also combined exposures from different sources with similar migration patterns are not likely to pose an unacceptable risk to consumers based on the findings in this study.”
Federal Register: Residues of Silver in Foods from Food Contact Surface Sanitizing Solutions; Exemption from the Requirement of a Tolerance
Spray silver disinfectant products are ruled safe for use on food contact surfaces by EPA.
History of the Medical Use of Silver
Silver has been used for at least six millennia to prevent microbial infections, and was the most important antimicrobial agent available before the introduction of antibiotics.
The Long History of Silver in Health and Healing
The germicidal properties of silver, although not recognized as such, have been utilized since the times of the ancient Mediterranean and Asiatic cultures.
Science Digest’s 1978 Article on Silver and Healing by Jim Powell
This is the famous, oft-quoted 1978 Science Digest article on silver and healing, by Jim Powell, in its entirety.
Activity of Colloidal Silver Preparations Towards Smallpox Virus
Colloidal silver demonstrated to be effective against smallpox virus.
Characterization of Antiplatelet Properties of Silver Nanoparticles
Silver nanoparticles prevent blood from clotting in animal model and in vitro.
Antitumor Activity of Colloidal Silver on MCF-7 Human Breast Cancer Cells
Will colloidal silver be the first big cure for breast cancer?
Toxicity of Nanosilver on Osteoblast Cancerous Cell Line
According to the authors of this study, published in the journal International Nano Letters (January 2011), nanosilver exhibited “broad spectrum inhibition” against the cancer cell line studied. The authors state, “Many attempts have been made to use silver nanoparticles as an anti-cancer agent and they have all turned up positive…The purpose of this study was to assess the biological assay of nanosilver (Nanocid®) on osteoblast (G292) cancerous cell line. The effect of nanosilver on these cells was evaluated by light microscopy, and by cell proliferation and standard cytotoxicity assays. The results demonstrate a concentration-dependent toxicity for the cell tested, and IC50 was determined 3.42 µg/mL, suggest(ing) that the product is more toxic to cancerous cells compared to other heavy metal ions.” The authors concluded, “In general, silver nanoparticles should serve as one of the best ways of treating diseases that involve cell proliferation and cell death.”
Antitumor Activity Of Silver Nanoparticles In Dalton’s Lymphoma Ascites Tumor Model
Study confirms the antitumor properties of silver nanoparticles, and suggest that they may be a cost-effective alternative in the treatment of cancer.
Viral Pathogens and Severe Acute Respiratory Syndrome: Oligodynamic Ag1 for Direct Immune Intervention
Retrospective study of silver-based therapeutics briefly reviews their history, and explores the modern application of charged silver particles as an antiviral agent.
A Mechanistic Study of the Antibacterial Effects of Silver Ions on Escherichia coli and Staphylococcus aureus
Researchers discover one of the ways silver ions destroy pathogens, i.e., by attaching to DNA and preventing the pathogen from replicating.
Effects of Electrically Generated Silver Ions on Human Cells and Wound Healing
Dr. Robert O. Becker’s classic study on healing wounds with electrically generated silver ions.
Antibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia coli
Electrically generated silver ions used in washing machines are shown to cause significant reductions in bacterial counts of Staph aureus and E. coli.
NASA Document on Silver Ionization Process for Water Purification on Manned Space Flights
Silver plays a key role in assuring safe water for manned space crews.
Silver News, 1st Quarter 2010, Nanosilver Overcomes Blood Platelet Disorders
Blood platelet aggregation is serious and can be life threatening; nanosilver may act as an effective anticoagulant.
Antibacterial Efficacy Studies of Silver Nanoparticles Against Escherichia coli ATCC-15224
Silver nanoparticles are shown to dramatically reduce E. coli bacterial counts.
Anti-bacterial Performance of Colloidal Silver-treated Laminate Wood Flooring
Colloidal silver-treated laminate wood flooring keeps the bacteria away.
Silver-Coated Nylon Fiber as an Antibacterial Agent
Silver-coated nylon fabric prevents infections in wounds.
Silver-Nylon: a New Antimicrobial Agent
Silver-coated nylon fabric prevents infections in wounds.
Bob Beck: Take Back Your Power
Dr. Bob Beck’s classic treatise on healing with electromedical devices and colloidal silver.
Bactericidal Activity of Combinations of Silver–Water Dispersion™ with 19 Antibiotics Against Seven Microbial Strains
The famous BYU study demonstrating the ability of a colloidal silver solution to boost the effectiveness of antibiotic drugs against drug-resistant microbes.
Antifungal Textiles Formed Using Silver Deposition in Supercritical Carbon Dioxide
Supercritical CO2 processing can be used to infuse textiles used in hospitals with silver nanoparticles, giving them profound antifungal properties.
Bactericidal Effect of Silver Nanoparticles Against Multidrug-resistant Bacteria
Silver nanoparticles shown to be effective broad-spectrum biocides against a variety of drug-resistant bacteria.
In Vitro Evaluation of the Activity of Colloidal Silver Concentrate Against Pseudomonas aeruginosa Isolated from Postoperative Wound Infection
Colloidal silver proven effective against multi-drug resistant Pseudomonas aeruginosa, one of the most deadly drug-resistant pathogens.
Colloidal Silver As a New Antimicrobial Agent
Colloidal silver was found to be effective against drug-resistant Staphylococcus aureus, Escherichia coli, Pseudomonas aregnosa and Salmonells typhi.
Colloidal Silver for Lung Disease in Cystic Fibrosis
An 11-year old Cystic Fibrosis victim with multi-drug resistant Burkholderia multivorans and Stenotrophomonas maltophilia responds to colloidal silver.
Ultrastructural Localization and Chemical Binding of Silver Ions in Human Organotypic Skin Cultures
The human body is demonstrated to have a specific method of neutralizing the potentially toxic in vitro effects of silver ions on human cells, utilizing the antioxidant glutathione.
Patent for Antiviral Colloidal Silver Composition
“We disclose a colorless composition comprising silver particles and water [manifesting] significant antimicrobial properties including antiviral properties.”
MTR Uses Silver Nano Technology to Enhance Hygiene Levels on Passenger Rail Lines
Japanese public railway line uses silver nanotechnology to keep contact surfaces free of pathogens
Induced Dedifferentiation: A Possible Alternative to Embryonic Stem Cell Transplants
Famous Robert O. Becker study demonstrating how electrically generated silver ions can produce tissue regeneration at wound site, or even limb regeneration, thus providing a potential morally acceptable alternative to embyronic stem cell transplants.
Therapeutic Properties of Silver: A Historical and Technical Review, by S.M. Foran
Even now, with over one hundred antibiotics available, there is a fear that many bacteria will become resistant to all antibiotics, plunging humanity back into the conditions that existed in the pre-antibiotic age. This study reviews the historical usage of silver and concludes that oligiodynamic silver in the form of silver ions may well be the answer to this most pressing of medical problems.
The Effect Of Silver Ions On The Respiratory Chain Of Escherichia Coli
Researchers demonstrate that silver ions inhibit the respiratory chain of E.coli, killing the pathogen.
Promising Cure for URTI Pandemics, Including H5N1 and SARS: Has the Final Solution to the Coming Plagues Been Discovered? (Part II), by Eric Gordon, MD and Kent Holtorf, MD
Drs Eric Gordon, MD and Kent Holtorf, MD make their case that oligodynamic silver hydrosol is the safe, natural solution to SARS and other potentially deadly viral pandemics.
Nanotechnology’s Latest Oncolytic Agent: Silver, Cancer & Infection Associations (Part III) By John Apsley, DC, Kent Holtorf, MD, Eric Gordon, MD, Wayne Anderson, ND, and Rashid Buttar, DO
Landmark studies over the past several decades have demonstrated that oligodynamic Ag+ could play a pivotal role in overcoming cancerous processes. This article reviews these findings and offers a proposal for future studies and protocol development.
Antibacterial Efficacy of Colloidal Silver Alone and in Combination With Other Antibiotics on Isolates from Wound Infections
Low dose colloidal silver kills antibiotic-resistant staph and E.coli, and does not interfere with therapeutic efficacy of prescription antibiotics tested.
Nanotechnology In Medicine And Antibacterial Effect Of Silver Nanoparticles
Silver nanoparticles demonstrated to be the answer to the increase in new resistant strains of bacteria against most potent antibiotics.
Microbial Multi-Drug Resistance (MDR) and Oligodynamic Silver
The idea of silver-resistance among pathogenic microbes is explored, and placed in proper context with actual facts in this white paper by the Immunogenic Research Foundation.
Exposure Related Health Effects of Silver and Silver Compounds — A Review
This critical review of the medical literature dating back to the early 1900’s demonstrates that it is soluble silver compounds such as silver nitrate, silver chloride, silver acetate, silver protein and others that are responsible for the vast majority of cases of skin-staining (i.e., argyria) reported in the medical literature. “Many researchers attribute the pigmentation process associated with generalized argyria solely to soluble silver compounds…”
Technical White Paper: Antimicrobial Activity of Silver (Is Largely Dependent Upon the Presence of Silver Ions)
The antibacterial activity of silver ions, metallic silver and silver nanoparticles is discussed in this Technical White Paper from Industrial Biological Services, Ltd. of Berkshire, England. The paper concludes that silver ions are the principle active antimicrobial species of silver, with metallic silver being relatively unreactive, and silver nanoparticles exhibiting size-dependent activity against both bacteria and viruses. The paper also concludes “The mechanism depends on both the concentration of silver ions present and the sensitivity of the microbial species to silver. Contact time, temperature, pH and the presence of free water all impact on both the rate and extent of antimicrobial activity. However, the spectrum of activity is very wide and the development of resistance relatively low, especially in clinical situations.”
Antifungal Properties of Electrically Generated Metallic Silver Ions
The well-known 1976 study by R.O. Becker, Berger, Spadaro, Bierman and Chapin, which demonstrated conclusively the powerful antifungal properties of electrically generated silver ions.
Colloidal Silver in Sepsis
The 1915 study published in the Transactions of the American Association of Obstetricians and Gynecologists, Vol. XXVIII, demonstrating electrically generated colloidal silver to be effective against blood-borne infections (i.e., sepsis).
Ammonia Hypothesis of Ionic Silver Utility In Vivo
This is the brilliant blow-by-blow refutation of Frank Key’s “silver chloride hypothesis” by Stuart Thomson, director of research at Gaia Research Institute. Thomson demonstrates that, contrary to Key’s assertion, hydrochloric acid in the stomach does not render ionic silver insoluble. Rather, naturally occurring ammonia in the human body — which plays an important role in health and well-being — acts as a solvent to diminish the bonding effects of hydrochloric acid on silver ions, and renders soluble again any silver bound as AgCl, both in the digestive tract and systemically. This report is excerpted from a long-running debate on The Silver List.
Everything You Ever Wanted to Know About the Use of Silver In Wound Therapy 2011
This is an impressive 2011 White Paper by Systagenix Wound Management, explaining the scientific basis for the use of silver dressings in wound management and clinical practice, and providing a general background on silver as an antimicrobial, including details on its mode of action, potential for resistance and safety profile, as well as an overview of the current available commercial silver dressings.
Silver Nanoparticles As Broad-spectrum Bactericidal and Virucidal Compounds
Another great study published in the September 2011 issue of the Journal of Nanobiotechnology, demonstrating the profound bactericidal and virucidal effectiveness of silver nanoparticles, along with implications for the use of AgNP’s against HIV and other viral pathogens.
Colloidal Silver Suspension for Treating Skin Problems in Tropical or Decorative Fish
This is a U.S. patent explaining a simple method for using colloidal silver to treat skin problems and topical infections in tropical or decorative fish, including the amounts of colloidal silver to add to the tank each day during treatment time, the level of silver that needs to be reached in the tank for maximum effectiveness, other necessary maintenance and care, as well as expected results.
Attenuation of Allergic Airway Inflammation and Hyper-responsiveness in a Murine Model of Asthma by Silver Nanoparticles
This is a groundbreaking clinical study concluding that silver nanoparticles might be effective in the prevention or treatment of asthma. According to the study authors, “Our study suggests that oxidative stress is an important determinant of allergic airway disease and that silver NPs attenuated oxidative stress in the murine asthma model. Also, by administration of silver NPs, Th2 inflammation, which is one of the main asthma-inducing immune factors, was significantly decreased. We suggest that silver NPs may be useful as a therapeutic strategy through their properties as antioxidant and anti-inflammatory agents.”
Silver Ion Water Sterilizer By Jowa
This company has installed it’s silver-based water disinfection systems on thousands of European merchant ships and cruise liners since the 1970s to help prevent bacterial contamination of the ship’s water supply. These units — operating on the same basic principle as a colloidal silver generator — have been in constant use for forty years, with the occasional replacement of the silver electrodes. Millions of people have drank the silver purified water — including crew members who drink it regularly.
Use of Silver Nanoparticles Increased Inhibition of Cell-Associated HIV-1 By Neutralizing Antibodies Developed Against HIV-1 Envelope Proteins
Another fascinating study published in the Journal of Nanobiotechnologydemonstrating that when silver nanoparticles are added to neutralizing antibodies (i.e., NABs) known to inhibit HIV-1 infection, the potency of the NABs is significantly increased, and HIV-1 transmission and infection is dramatically inhibited. The researchers are apparently working toward developing an antiviral vaginal cream that utilizes silver and NABs to help protect women from becoming infected by an HIV positive partner.
Novel Microfilaricidal (Anti-Parasite) Activity of Nanosilver
This clinical study found that nanosilver has potent anti-parasite effects against the larval stage of the parasite Brugia malayi, a roundworm which infects millions of people in India, China and throughout southeast Asia. The parasite causes a disease known as elephantitis (i.e., elephantiasis), which is characterized by intense and sometimes grotesque swelling of the legs. This may be the first time that silver has been clinically demonstrated to be effective against parasites in any stage beyond the egg stage. The researchers also found nanosilver to be safe when used against this parasite.
Silver Colloidal Nanoparticles: Antifungal Effect Against Adhered Cells and Biofilms of Candida albicans and Candida glabrata
In this important 2011 study, researchers demonstrate that “silver colloidal nanoparticles” not only have a profound antifungal effect on two forms of Candida, but is also effective in destroying the biofilms produced by these fungal pathogens. Biofilms allow pathogens to adhere to cell walls and help protect them from the immune system and any natural predators in the human body. So this is an important new study, because in many cases biofilms are what stymie modern drug-based therapies from actually getting to the pathogen. Thankfully, silver seems to have no problem busting through the biofilms.
Oral Thrush and Dental Stomatitis: Preliminary Research to Determine if Silver Nanoparticles in Mouthwash and Dentures Might Stop These Infections
In a 2012 study published in Letters in Applied Microbiology, Professor Henriques and her team looked at the use of different sizes of silver nanoparticles to determine their anti-fungal properties against Candida albicans and Candida glabrata. These two yeasts cause infections including oral thrush and dental stomatitis, a painful infection affecting around seven out of ten denture wearers. Infections like these are particularly difficult to treat because the microorganisms involved form biofilms. Professor Henriques comments: “With the emergence of Candida infections which are frequently resistant to the traditional antifungal therapies, there is an increasing need for alternative approaches. So, silver nanoparticles appear to be a new potential strategy to combat these infections. As the nanoparticles are relatively stable in liquid medium they could be developed into a mouthwash solution in the near future.”
Antifungal Effect of Silver Nanoparticles on Dermatophytes
Here’s an interesting clinical study demonstrating the effectiveness of silver nanoparticles against the pathogen most commonly responsible for toenail fungus. According to the study, “Spherical silver nanoparticles (nano-Ag) were synthesized and their antifungal effects on fungal pathogens of the skin were investigated. Nano-Ag showed potent activity against clinical isolates and ATCC strains of Trichophyton mentagrophytes and Candida species. The activity of nano-Ag was comparable to that of amphotericin B, but superior to that of fluconazole. Additionally, we investigated their effects on the dimorphism of Candida albicans. The results showed nano-Ag exerted activity on the mycelia. Thus, the present study indicates nano-Ag may have considerable antifungal activity, deserving further investigation for clinical applications.”
Mode of Antiviral Action of Silver Nanoparticles Against HIV-1
Silver nanoparticles have proven to exert antiviral activity against HIV-1 at non-cytotoxic concentrations, but the mechanism underlying their HIV-inhibitory activity has not been not fully elucidated. In this study, silver nanoparticles are evaluated to elucidate their mode of antiviral action against HIV-1 using a panel of different in vitro assays. Results: Our data suggest that silver nanoparticles exert anti-HIV activity at an early stage of viral replication, most likely as a virucidal agent or as an inhibitor of viral entry. Silver nanoparticles bind to gp120 in a manner that prevents CD4-dependent virion binding, fusion, and infectivity, acting as an effective virucidal agent against cell-free virus (laboratory strains, clinical isolates, T and M tropic strains, and resistant strains) and cell-associated virus. Besides, silver nanoparticles inhibit post-entry stages of the HIV-1 life cycle. Conclusions: These properties make them a broad-spectrum agent not prone to inducing resistance that could be used preventively against a wide variety of circulating HIV-1 strains.
Topical Delivery of Silver Nanoparticles Promotes Wound Healing
According to the study authors, “We investigated the wound-healing properties of silver nanoparticles in an animal model and found that rapid healing and improved cosmetic appearance occur in a dose-dependent manner. Furthermore, through quantitative PCR, immunohistochemistry, and proteomic studies, we showed that silver nanoparticles exert positive effects through their antimicrobial properties, reduction in wound inflammation, and modulation of fibrogenic cytokines. These results have given insight into the actions of silver and have provided a novel therapeutic direction for wound treatment in clinical practice.”
Silver Nanoparticles as Potential Antiviral Agents
From the clinical journal Molecules, a review of studies demonstrating the potent antiviral effects of silver nanoparticles against HIV-1, hepatitis B virus, herpes simplex virus, respiratory syncytial virus and monkey pox virus, and concluding that silver and other metal nanoparticles may provide opportunity to develop novel antiviral therapies with lower levels of resistance compared to conventional antiviral drugs.
Silver Nano – A Trove for Retinal Therapies
Silver nanoparticles are being discovered to have profound therapeutic properties in certain diseases of the eyes that can result in visual impairment or even irreversible blindness. This clinical study review shows that silver nanoparticles may play a successful role in reversing pathological retinal angiogenesis (neovascularization), one of the most feared complications among retinal diseases. According to the study authors, “Recent findings made by us on therapeutic applications of biologically synthesized silver nanoparticles (AgNPs) against VEGF induced retinal endothelial cells, elucidates the effectual inhibitory activities of AgNPs over the downstream signaling pathways (Src and AKT/PI3K) leading to retinal angiogenesis.” The researchers concluded that present clinical research “consequently affirms the futuristic application of silver nanoparticles as a boon to ocular therapies.”
Silver Nanoparticles Impede Biofilm Formation By Pseudomonas aeruginosa and Staphylococcus epidermidis
Pathogens that form biofilms are among the most frustrating for doctors to deal with because the protective barrier the microbes are able to erect around themselves is difficult for antibiotic drugs to penetrate. The result is often relentless and chronic infection. In this clinical study researchers found that silver nanoparticles impede the formation of the biofilm barriers normally erected by Pseudomonas aeruginosa and Staphylococcus epidermidis. According to the study authors, “Treating these organisms with silver nanoparticles resulted in more than 95% inhibition in biofilm formation. The inhibition was known to be invariable of the species tested. As a result this study demonstrates the futuristic application of silver nanoparticles in treating microbial keratitis based on its potential anti-biofilm activity.”
Venereal Diseases: Their Treatment and Cure
This is an older clinical report from the early 1900’s by Dr. Omar Wilson, M.D., and published in a journal called The Canadian Medical. Dr. Wilson discusses his success with the use of a colloidal silver protein compound known as Protargol, which he had found to be an astonishingly helpful treatment for gonorrhea when instilled into the urethra of the penis, followed by prostatic massage where appropriate. Says Dr. Wilson in his report, “Some years ago I was afforded the opportunity of experimenting with germicidal preparations in gonorrhea. After prolonged experiments I became convinced that Protargol gave the best results, and curiously enough, that one-half percent Protargol was remarkably more efficient than solutions of greater strength.”
Bactericidal Actions of a Silver Ion Solution on Escherichia coli, Studied by Energy-Filtering Transmission Electron Microscopy and Proteomic Analysis
In this study, published in November 2005 in the journal, Applied and Environmental Microbiology, researchers examined the bactericidal function of silver ions, using Escherichia coli as a model microorganism. The researchers found that the silver ion readily infiltrates the interior of E. coli, rather than residing in the cell membrane area and affecting the function of membrane-bound enzymes, as was previously theorized. According to the study authors, “The present results indicate that one of the major bactericidal actions of the silver ion is caused by its interaction with the ribosome and subsequent suppression in the expression of enzymes and proteins essential to ATP production.” In other words, the silver ions infiltrate the bacterial cell and destroy the ability of the bacteria to generate life-giving energy from the inside.
Treatment of Orthopaedic Infections with Electrically Generated Silver Ions
The famous clinical study by Dr. Robert O. Becker, M.D., and Joseph A. Spadaro, Ph.D., on healing bone non-unions and infected wounds with electrically generated silver ions. The study was published in 1978 in theJournal of Bone and Joint Surgery. The researchers used pure silver wire in some cases, and silver mesh in others, hooked up to a low-voltage electrical apparatus to deliver a steady stream of silver ions into the wound site. The researchers report in most cases that all infectious microorganisms were killed by the silver, and dramatic healing and even bone union took place. The researchers concluded, “Silver would appear to be the metal of choice for implanted electrodes used for bone stimulation. Its antibacterial properties, when it is the anode, would assist in controlling a quiescent pre-existing or operatively acquired infection. The results obtained with the silver-nylon electrode in open osteomyelitis would appear to warrant further investigation of its usage as an antibacterial dressing after wound debridement.”
The Antimicrobial Efficacy of Silver on Antibiotic-Resistant Bacteria Isolated From Burn Wounds
In this clinical study conducted by researchers from the Department of Pathology at West Virginia University, researchers found that when silver-ion emitting wound dressings containing two different kinds of silver compounds were exposed to a wide range of antibiotic-resistant bacteria, environments with lower pH (i.e., increased acidity) resulted in significantly greater antimicrobial activity compared to environments with higher pH (i.e., increased alkalinity). According to the researchers, “…when pH was changed from 8.5 to 5.5 antimicrobial activity for both dressings in general increased significantly (P < 0.05)… the study showed that the performance of both dressings apparently increased when pH became more acidic. The findings in this study may help to further enhance our knowledge of the role pH plays in affecting both bacterial susceptibility and antimicrobial activity of silver containing wound dressings.”
Antimicrobial Activity of Colloidal Silver Nanoparticles Prepared by Sol-Gel Method
In this clinical study, published in the Digest Journal of Nanomaterials and Biostructures, researchers from the Metallurgical and Material Science Engineering Department at Dokuz Eylul University in Turkey documented that colloidal silver nanoparticles in very low concentrations (i.e., 2-4 ppm) and at particle sizes of approximately 20-45 nm demonstrated a pronounced antibacterial effect against Escherichia coli, Staphylococcus aureus, Candida albicans, Bacillus subtilis, Salmonella typhimurium, Pseudomonas aeruginosa and Klebsiella pneumoniae.
Silver Nanoparticles Effective Against Tuberculosis Bacteria
In this study abstract, entitled “Nature-inspired novel drug design paradigm using nanosilver: efficacy on multi-drug-resistant clinical isolates of tuberculosis” the authors state that by capping silver nanoparticles with bovine serum albumin and then testing it in the laboratory against “clinical isolates collected from TB endemic areas” (i.e., sputum samples collected from pulmonary TB patients) they were able to demonstrate that this novel nanosilver compound constitutes a “potent anti-TB drug.” In the full study, which is available through the journal Current Microbiology (2011, 62:715-726), the authors further state, “Encouragingly, the results indicate that this novel design could be further extended for developing improved medicinal agents for combating multi-drug-resistant TB.”
The Silver Nanoparticle (Nano-Ag): A New Model for Antifungal Agents
In this study from the School of Life Sciences and Biotechnology, College of Natural Sciences, Kyungpook National University, Republic of Korea, silver nanoparticles were prepared and tested against clinical isolates of T. mentagrophytes and Candida fungal pathogens. The study authors conclude, “Nano-Ag also exhibited potent antifungal effects, probably through destruction of membrane integrity. To the author’s knowledge, this is the first study to apply Nano-Ag successfully to dermatophytes and pathogenic fungal strains. Secondly, the fact that preparation method of Nano-Ag described here is cost-effective is also of importance. Therefore, it can be expected that Nano-Ag may have potential as an anti-infective agent for human fungal diseases.”
Antifungal Activity and Mode of Action of Silver Nano-particles on Candida Albicans
In this abstract of a study conducted at the Department of Microbiology, College of Natural Sciences, at Kyungpook National University in South Korea, and published in the journal Biometals, researchers studied the anti-fungal effects of silver nano-particles and investigated their mode of action. The study authors concluded, “The results suggest nano-Ag may exert an antifungal activity by disrupting the structure of the cell membrane and inhibiting the normal budding process due to the destruction of the membrane integrity. The present study indicates nano-Ag has considerable antifungal activity, deserving further investigation for clinical applications.
Antifungal Effects of Silver Nanoparticle Alone and With Combination of Antifungal Drug on Dermatophyte Pathogen Trichophyton Rubrum
In this clinical study conducted at the Department of Biology, Islamic Azad University, and published by the 2011 International Conference on Bioscience, Biochemistry and Bioinformatics, researchers examined the effects of silver nanoparticles — alone, and in combination with two well-known anti-fungal drugs — on the dermatophyte fungi Trichophyton rubrum. The study authors found that “results of antifungal activity reveal that the growth of T. rubrum was inhibited at concentration of 10 µg/ml Ag-Nps alone.” The study authors also found that the antifungal activity of the drugs Flocunazole and Geriseofulvin were “increased in the presence of Ag-NP’s.” In short, silver nanoparticles demonstrated significant antifungal activity on their own, and when used in combination with antifungal drugs, they increased the antifungal efficacy of the drugs.
Antibacterial Activity and Mechanism of Silver Nanoparticles onEscherichia coli
In this clinical study conducted at the Guangdong Institute of Microbiology at Guangzhou, China, and published in 2010 in Applied Microbiology and Biotechnology, the researchers studied the antibacterial activity of silver nanoparticles against E. coli, as well as the mechanism through which silver nanoparticles provided inhibitory and bactericidal effects. The authors state, “The combined results suggest that silver nanoparticles may damage the structure of the bacterial cell membrane and depress the activity of some membranous enzymes, which cause E. coli bacteria to die eventually… For the first time, we offer evidences to indicate that silver nanoparticles can inhibit bacterial growth and even kill the cells through destroying bacterial membranous structure and permeability.”
Silver Nanoparticles Neutralize Hemorrhagic Fever Viruses
This is a recently unclassified presentation produced by the U.S. Department of Defense’s (DOD) Defense Threat Reduction Agency (DTRA) and the U.S. Strategic Command (USSTRATCOM) Center for Combating Weapons of Mass Destruction. It demonstrates the powerful neutralizing effects of silver nanoparticles against hemorrhagic fever viruses, including Arenavirus and Filovirus (i.e., Ebola). One of the main tasks of the DOD’s Defense Threat Reduction Agency is to “anticipate and mitigate future threats long before they have a chance to harm the United States and our allies.” The presentation was given by researchers from the Applied Biotechnology Branch, 711th Human Performance Wing of the Air Force Research Laboratory. The researchers concluded that in vitro, silver nanoparticles neutralize hemorrhagic fever viruses inside the cells by decreasing S segment gene expression and concomitantly decreasing progeny virus production. They note that viral neutralization occurs during the early phases of viral replication, so silver nanoparticle treatment would have to be administered prior to viral infection or within the first two to four hours after initial virus exposure.
Interaction of Silver Nanoparticles With Tacaribe Virus
Silver nanoparticles possess many unique properties that make them attractive for use in biological applications. An area that has been largely unexplored is the interaction of nanomaterials with viruses and the possible use of silver nanoparticles as an antiviral agent. This research focuses on evaluating the interaction of silver nanoparticles with a New World arenavirus, Tacaribe virus, to determine if they influence viral replication. This suggests that the mode of action of viral neutralization by silver nanoparticles occurs during the early phases of viral replication.
Role of Silver Ions in Destabilization of Intermolecular Adhesion Forces Measured by Atomic Force Microscopy in Staphylococcus epidermidis Biofilms
In this study published in the journal Antimicrobial Agents and Chemotherapy (Dec. 2005, American Society for Microbiology) it was revealed that Staphylococci epidermis biofilms have been found to be “markedly impaired” by very low, non-inhibitory levels of silver ions. This is important news, since biofilms give communities of microorganisms a distinct ability to resist antibiotic drugs. If low levels of silver ions can impair biofilms, then its use may well help resolve one factor in the growing problem of antibiotic-resistant microorganisms. According to the study authors, “Our AFM studies on the intermolecular forces within the EPSs of S. epidermidis RP62A and S. epidermidis 1457 biofilms suggest that the silver ions can destabilize the biofilm matrix by binding to electron donor groups of the biological molecules. This leads to reductions in the number of binding sites for hydrogen bonds and electrostatic and hydrophobic interactions and, hence, the destabilization of the biofilm structure… After the addition of silver ions and within 60 min of contact, the overall structure of the biofilm became partially destroyed and the inner structure of biofilm was exposed. There were also significant amounts of EPSs around the damaged biofilm colony, confirming the effect of silver ions on the grown biofilm matrix”
Axen 30 Ionic Colloidal Silver Solution Kills Campylobacter Jejuni in Minutes
Axen 30, a commercial disinfectant product consisting of a stabilized form of electrically generated ionic silver, demonstrated efficacy againstCampylobacter jejuni and therefore meets the requirements set forth by the U.S. EPA for disinfectant label claims. This essentially means the ionic silver solution killed this well-known food poisoning bacteria within exposure periods of two and five minutes. The EPA efficacy performance requirements for label claims state that the disinfectant must kill the microorganism on 10 out of 10 inoculated carriers or the label claims cannot be approved. According to the study conclusion, “Under the conditions of this investigation, Axen 30…demonstrated efficacy against Campylobacter jejuni as required by the U.S. EPA for disinfectant label claims following two and five minute exposure periods.”
A Pharmacological and Toxicological Profile of Silver as an Antimicrobial Agent in Medical Devices
This is an impressive review of the available medical data regarding the pharmacology and toxicology of silver used as an antimicrobial agent in medical devices. Published in the journal Advances in Pharmacological Sciences, and written by Alan B. G. Lansdown, the well-known British researcher and author of the definitive guide to the use of silver in medical situations, Silver in Healthcare: It’s Antimicrobial Efficacy and Safety in Use(Issues in Toxicology, RSC Publishing). The review concludes, in part, “Silver should not be regarded as a cumulative poison…Only in cases of chronic systemic silver overload situations where excretory mechanisms become saturated, does silver deposit in an inert fashion in lysosomal or intercellular sites, unrelated to tissue damage. In these situations, selenium serves as a major protective factor in precipitating the silver in a highly insoluble and hence inert form of silver selenide.”
Silver In Drinking Water — World Health Organization Guidelines
In this report the World Health Organization discusses the maximum allowable amount of silver allowed in drinking water, and reports that the “biological half-life (of silver) in humans ranges from several days to 50 days. According to the report, the liver plays the main role in the elimination of silver from the body. And most ingested silver is excreted in the feces, with cumulative excretion rates between 90-99%. The report states, “The only known clinical picture of chronic silver intoxication is that of argyria, a condition in which silver is deposited on skin and hair, and in various organs following occupational or iatrogenic exposure to metallic silver and its compounds, or the misuse of silver preparations.” The report concludes, “On the basis of present epidemiological and pharmacokinetic knowledge, a total lifetime oral intake of about 10 g of silver can be considered as the human NOAEL [i.e., No Observable Adverse Effect Level]…Higher levels of silver, up to 0.1 mg/litre (a concentration that gives a total dose over 70 years of half the human NOAEL of 10 g), could then be tolerated without risk to health.”
Toxicological Profile for Silver — Agency for Toxic Substances and Disease Registry
In this U.S. Public Health Service report from the Agency for Toxic Substances and Disease Registry, the health and toxicological effects of silver ingested or absorbed through various means are examined. The report states that most of the silver that is eaten or breathed in leaves the body in the feces within about a week. And that argyria (i.e., skin discoloration) is the “most serious heath effect” of excessive silver exposure. According to the report, “It is likely that many exposures to silver are necessary to develop argyria. Once you have argyria it is permanent. However, the condition is thought to be only a ‘cosmetic’ problem. Most doctors and scientists believe that the discoloration of the skin seen in argyria is the most serious health effect of silver.” The report concludes, “Populations that are unusually susceptible to toxic effects of silver exposure are those that have a dietary deficiency of vitamin E or selenium, or that may have a genetically based deficiency in the metabolism of these essential nutrients. Individuals with damaged livers may also be more susceptible to the effects of silver exposure. In addition, populations with high exposures to selenium may be more likely to develop argyria. Furthermore, some individuals may exhibit an allergic response to silver.”
The Effect of Nano-Silver Liquid against the White Rot of the Green Onion Caused by Sclerotium cepivorum
In this breakthrough study, published in the March 2010 issue of the journalMycobiology, researchers found that applying varying levels of silver nanoparticles to the roots of green onion plants completely eradicatedSclerotium cepivorum fungal infections known to destroy the plants. Not only did the application of silver nanoparticles destroy the pathogenic plant fungus, but according to the study authors, it caused no harm whatsoever to beneficial soil microbes needed by the green onion plants for growth, nor was there any negative change in the soil chemistry or composition. What’s more, the nanosilver-treated green onion plants, once harvested, were demonstrated to have grown larger and to weigh more than the non-treated green onion plants. Finally, the study researchers pointed out that the more they increased the use of nanosilver on the green onion plants, the lower the level of silver being absorbed into the plant itself. The researchers stated, “When the amount of nano-silver was calculated in the plants grown in nano-silver treated soil, it was found that the concentration of nano-silver used for treatment and the concentration of nano-silver found in the plants was inversely proportional.” In other words, the plants themselves apparently reduce absorption of the nanosilver when higher levels are used on them to control the plant blight. The conclusion drawn by the study researchers was staggering in its implications: “Nano-silver liquid for the prevention of various plant pathogenic fungi is highly recommended to farmers. Additionally, the use of nano-silver does not cause any harm to human beings, and it is safe for the environment and agricultural products. In conclusion, we can say that by using nano-silver liquid, environmental pollution and the excessive use of chemical compounds in the field can be reduced. It is expected that the application of nano-silver at low concentrations will be economic, eco friendly, and decrease farm management costs.”
Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria
In this June 2013 clinical study published in the journal Science Translational Medicine, titled “Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria,” it was documented by the study authors that antimicrobial silver could be used to help restore the effectiveness of antibiotic drugs by up to 1,000%. The authors state, “We show that silver disrupts multiple bacterial cellular processes, including disulfide bond formation, metabolism, and iron homeostasis. These changes lead to increased production of reactive oxygen species and increased membrane permeability of Gram-negative bacteria that can potentiate the activity of a broad range of antibiotics against Gram-negative bacteria in different metabolic states, as well as restore antibiotic susceptibility to a resistant bacterial strain.” The authors also revealed that silver-treated bacteria weren’t even able to produce a biofilm, and that when drug-resistant biofilms were treated with silver, the bacterial resistance to antibiotic drugs was negated. Finally, the silver/antibiotic drug combinations tested were able to eradicate bacterial persister cells which can otherwise result in multi-drug tolerance and relapsing chronic infections.
Silver In Health Care: Antimicrobial Effects and Safety In Use
This study, published in the journal Current Problems in Dermatology (2006;33:17-34) is by one of Britain’s top experts in antimicrobial silver, Alan B. Lansdown of the Imperial College Faculty of Medicine, Charing Cross Hospital in London, UK. He writes, “Silver has a long and intriguing history as an antibiotic in human health care. It has been developed for use in water purification, wound care, bone prostheses, reconstructive orthopaedic surgery, cardiac devices, catheters and surgical appliances. Advancing biotechnology has enabled incorporation of ionizable silver into fabrics for clinical use to reduce the risk of nosocomial infections and for personal hygiene. The antimicrobial action of silver or silver compounds is proportional to the bioactive silver ion (Ag(+)) released and its availability to interact with bacterial or fungal cell membranes…. Silver exhibits low toxicity in the human body, and minimal risk is expected due to clinical exposure by inhalation, ingestion, dermal application or through the urological or haematogenous route. Chronic ingestion or inhalation of silver preparations (especially colloidal silver) can lead to deposition of silver metal/silver sulphide particles in the skin (argyria), eye (argyrosis) and other organs. These are not life-threatening conditions but cosmetically undesirable. Silver is absorbed into the human body and enters the systemic circulation as a protein complex to be eliminated by the liver and kidneys. Silver metabolism is modulated by induction and binding to metallothioneins. This complex mitigates the cellular toxicity of silver and contributes to tissue repair. Silver allergy is a known contra-indication for using silver in medical devices or antibiotic textiles.”
Inhibitory Effects of Silver Nanoparticles on H1N1 Influenza A Virus In Vitro
In this study, published in the Journal of Virological Methods in December 2011, the study authors concluded that silver nanoparticles were able to inhibit H1N1 influenza A virus. According to the study authors, “In this study, the interaction of silver nanoparticles with H1N1 influenza A virus was investigated…This study demonstrates that silver nanoparticles have anti-H1N1 influenza A virus activities. The inhibitory effects of silver nanoparticles on influenza A virus may be a novel clinical strategy for the prevention of influenza virus infection during the early dissemination stage of the virus.”
Silver Nanoparticles Inhibit Hepatitis B Virus Replication
In this study, published in the journal Antiviral Therapy in 2008, researchers from the Department of Medicine, University of Hong Kong, demonstrated the silver nanoparticles could be used to inhibit the replication of hepatitis B virus due to the ability to bind with the viral DNA. According to the study authors, “Silver nanoparticles have been shown to exhibit promising cytoprotective activities towards HIV-infected T-cells; however, the effects of these nanoparticles towards other kinds of viruses remain largely unexplored. The aim of the present study was to investigate the effects of silver nanoparticles on hepatitis B virus (HBV)…. The in vitro anti-HBV activities of these particles were determined using the HepAD38 cell line as infection model… an absorption titration assay showed that the nanoparticles have good binding affinity for HBV DNA… we found that Ag10Ns could directly interact with the HBV viral particles as revealed by transmission electronic microscopy.” The study authors concluded, “Silver nanoparticles could inhibit the in vitro production of HBV RNA and extracellular virions. We hypothesize that the direct interaction between these nanoparticles and HBV double-stranded DNA or viral particles is responsible for their antiviral mechanism.”
Inactivation of Microbial Infectiousness By Silver Nanoparticles-Coated Condom: A New Approach to Inhibit HIV- and HSV-Transmitted Infection
In this remarkable study published in the International Journal of Nanomedicine in 2012, the study authors found that coating condoms with silver nanoparticles helped inhibit the infectivity of both HIV (i.e., Human Immunodeficiency Virus) and HSV (i.e., Herpes simplex virus), as well as bacterial and fungal microbes. The study authors stated, in part, “Recent research suggests that today’s condoms are only 85% effective in preventing human immunodeficiency virus (HIV) and other sexually transmitted diseases. In response, there has been a push to develop more effective ways of decreasing the spread of the disease. The new nanotechnology-based condom holds the promise of being more potent than the first-generation products. The preliminary goal of this study was to develop a silver nanoparticles (Ag-NPs)-coated polyurethane condom (PUC) and to investigate its antimicrobial potential including the inactivation of HIV and herpes simplex virus (HSV) infectiousness… No significant toxic effects was observed when human HeLa cells, 293T and C8166 T cells were contacted to Ag-NPs-coated PUC for three hours. Interestingly, our results demonstrated that the contact of the Ag-NPs-coated PUC with HIV-1 and HSV-1/2 was able to efficiently inactivate their infectiousness… Furthermore, we also showed that the Ag-NPs-coated PUC was able to inhibit the growth of bacteria and fungi. These results demonstrated that the Ag-NPs-coated PUC is able to directly inactivate the microbe’s infectious ability and provides another defense line against these sexually transmitted microbial infections.”
In vitro Antifungal Activity of Silver Nanoparticles Against Ocular Pathogenic Filamentous Fungi
In this study, published in the Journal of Ocular Pharmacology and Therapeutics in March 2013, the study authors focused on determining whether or not silver nanoparticles could be used as an effective treatment for fungal keratitis, which is emerging as a “major cause of vision loss” in China and other developing nations due largely to the unavailability of effective antifungals. According to the study authors, “It is urgent to explore broad-spectrum antifungals to effectively suppress ocular fungal pathogens, and to develop new antifungal eye drops to combat this vision-threatening infection. The aim of this study is to investigate the antifungal activity of silver nanoparticles (nano-Ag) in comparison with that of natamycin against ocular pathogenic filamentous fungi in vitro… Susceptibility tests were performed against 216 strains of fungi isolated from patients with fungal keratitis.” The researchers concluded that silver nanoparticles “…exhibit potent in vitro activity against ocular pathogenic filamentous fungi”.
Clinical Observation of Gelatamp Colloidal Silver Gel Sponge on the Treatment of Pericoronitis
In this clinical study, published in the International Journal of Stomatology in 2010 (Vol. 37, Issue 3), researchers using a colloidal silver gelatin sponge called Gelatamp studied 227 patients with third molar pericoronitis, which is an infection and inflammation of the soft tissues, gingiva and dental follicle around the molar tooth. They divided the patients up into two groups, one of which received treatment with the Gelatamp oral colloidal silver gelatin sponge used in the deep soft tissue pocket around the tooth, and the other using Iodine Glycerol in the soft tissue pocket, instead. According to the study authors, “The clinical effects were evaluated….Group Gelatamp colloidal silver gelatin sponge had better clinical effects than group Iodine Glycerol…Gelatamp colloidal silver gelatin sponge…effectively improved the clinical symptom and clinical results.”
Colloidal Silver Fabrication Using the Spark Discharge System and Its Antimicrobial Effect on Staphylococcus aureus
In this study, published in the journal Medical Engineering & Physics, the researchers used a unique method to create a stable colloidal silver solution consisting of both silver nanoparticles and silver ions. The solution was then tested for antimicrobial effect against Staphylococcus aureus. According to the study authors “Traditional chemical synthesis methods for colloidal silver may lead to the presence of toxic chemical species or chemical residues, which may inhibit the effectiveness of colloidal silver as an antibacterial agent. To counter these problems a spark discharge system (SDS) was used to fabricate a suspension of colloidal silver in deionized water with no added chemical surfactants.” This resulted in a solution that “contains both metallic silver nanoparticles and ionic silver foms.” The researchers then studied the antimicrobial effects of this solution on the Staph pathogen. They concluded, “The results show that colloidal silver solutions with an ionic silver concentration of 30 ppm or higher are strong enough to destroy S. aureus. In addition, it was found that a solution’s antimicrobial potency is directly related to its level of silver ion concentration.” In other words, the silver ions were found to be the active, infection-fighting specie of silver.
Spectrum of Antimicrobial Activity Associated With Ionic Colloidal Silver
In this study, published in the Journal of Alternative and Complementary Medicine in March 2013, researchers tested an ionic colloidal silver product against “several strains of bacteria, fungi, and viruses” that were “grown under multicycle growth conditions in the presence or absence of ionic colloidal silver in order to assess the antimicrobial activity.” According to the researchers, “…the Food and Drug Administration currently does not recognize colloidal silver as a safe and effective antimicrobial agent. The goal of this study was to further evaluate the antimicrobial efficacy of colloidal silver.” The researchers found that “significant inhibition was observed” for bacteria grown under aerobic (oxygen rich) or anaerobic (oxygen poor) conditions. However, the effect of the ionic silver “varied significantly” on fungal cultures, depending upon the strain or genera of fungus treated. And no viral growth inhibition was observed for the viruses tested. The study authors concluded, “The study data support ionic colloidal silver as a broad-spectrum antimicrobial agent against aerobic and anaerobic bacteria, while having a more limited and specific spectrum of activity against fungi.”
Anti-Leishmanial Effect of Silver Nanoparticles and their Enhanced Anti-Parastic Activity Under UV Light
According to this clinical study, published in the International Journal of Nanomedicine in November 2011, researchers found for the first time that silver nanoparticles are effective against the Leishmaniasis pathogen — a protozoan parasite that causes Leishmaniasis, a disease that is potentially fatal if left untreated, and which causes ulcers of the skin, mouth and nose, plus fever, anemia and enlarged spleen and liver. Leishmaniasis is currently endemic in 98 countries worldwide, affecting some 12 million people. The researchers demonstrated that silver nanoparticles significantly inhibited the infectivity of the Leishmaniasis pathogen, “inhibiting all biological activities of the parasite.” The study authors concluded, “Therefore, the authors consider a new approach, one that includes the application of Ag-NPs on vectors that carry infective Leishmania promastigotes, may be offered in the near future, and that this may prevent the disease from spreading… The results clearly show there is no need to apply high concentrations of Ag-NPs for inhibiting amastigotes, and this may be very promising for the treatment of leishmaniasis…Since leishmaniasis is spreading rapidly worldwide and because anti-leishmanial drugs have several disadvantages, the authors posit that treatment based on silver nanoparticles may have a very important role in overcoming leishmaniasis.”
Colloidal Silver Nanoparticles for the Prevention of Gastrointestinal Bacterial Infections
In this clinical study, published in the journal Advances in Natural Sciences: Nanoscience and Technology, researchers found that colloidal silver nanoparticles were extremely effective against two key forms of gastrointestinal bacteria responsible for serious infections, i.e., Escherichia coli (ATCC 43888-O157:k-:H7) and Vibrio cholera (O1). The research team demonstrated that the silver solution provided stronger and longer-lasting surface disinfection than conventional chemical disinfectants and surmised it could be effectively used in place of them. The researchers concluded, “In this work, we investigated the antibacterial and disinfectant activity of colloidal silver NPs which were prepared by a UV-enhanced photochemical method….It was found that our silver NPs colloid exhibited strongly effective antibacterial effect against tested gastrointestinal bacteria at a silver concentration as low as ~3 mg l-1. Interestingly, the silver NPs colloid displayed enhanced antimicrobial performance and longer lasting disinfectant effect as compared to the conventional chloramin B disinfection agent. With these exhibited advantages, the as-prepared colloidal silver NPs are very promising for use in treatment of environments containing gastrointestinal bacteria or other infectious pathogens.”
Rice University: Ions, Not Particles, Make Silver Toxic to Bacteria
In this press release from Rice University, clinical researchers discuss the results of their new study titled “Negligible Particle-Specific Antibacterial Activity of Silver Nanoparticles,” which was published in the July 5, 2012 issue of the journal Nano Letters. In their study, the researchers demonstrate conclusively that silver ions, and not metallic silver particles (i.e., nanosilver) are what make silver toxic to bacteria. The researchers found that the metallic (i.e., nanoparticle) form of silver is largely inert, and cannot kill pathogens except to the extent in sheds silver ions in the presence of pathogens. According to the study abstract, “For nearly a decade, researchers have debated the mechanisms by which AgNPs exert toxicity to bacteria and other organisms. The most elusive question has been whether the AgNPs exert direct ‘particle-specific’ effects beyond the known antimicrobial activity of released silver ions (Ag+). Here, we infer that Ag+ is the definitive molecular toxicant. We rule out direct particle-specific biological effects by showing the lack of toxicity of AgNPs when synthesized and tested under strictly anaerobic conditions that preclude Ag(0) oxidation and Ag+ release.”
Colloidal Silver: A Novel Treatment for Staphylococcus aureusBiofilms
In this study, published in the journal International Forum of Allergy & Rhinology in March 2014, the study authors begin by explaining that a patient with a “previously recalcitrant Staphylococcus aureus-infected chronic rhinosinusitis” began using a colloidal silver product as a nasal spray, and experienced marked improvement. The study authors then decided to test “whether colloidal silver has any direct bactericidal effects on these biofilms in vitro.” In other words, they wanted to see for themselves if colloidal silver killed Staphylococcus aureus under strict laboratory conditions. The researchers used various dilutions of colloidal silver. What they discovered was that except for the very lowest dilution used, the colloidal silver dramatically reduced the S. aureus biomasses. “At 20 uL colloidal silver, the reduction in biomass was 98.9%…a maximum biomass reduction of 99.8% was reached at both 100 and 150 uL colloidal silver. The study authors concluded, “Colloidal silver directly attenuates in vitro S. aureus biofilms.”


Eye Infections and colloidal silver

Using Colloidal Silver to Heal Eye Infections

Can colloidal silver be used safely in the eyes, to treat eye infections, sore eyes, itchy red eyes, sties, cataracts and more?

According to Dr. James Balch, M.D., author of the bestselling bookPrescriptions for Nutritional Healing, you can indeed use colloidal silver directly in your eyes for Pink Eye and other eye infections (i.e., conjunctivitis).
In his newsletter, he recommended a few drops in each eye, several times a day, of 5 ppm to 10 ppm colloidal silver.
Many years ago, when our son Ron was sent home from school with Pink Eye, the school nurse called to tell us it was a particularly virulent strain and was going around the school. She asked us to keep him home for several days so as to help prevent the spread of the infection.

We started putting a few drops of colloidal silver into each eye periodically throughout the afternoon, and by the next day it was completely cleared up and he was back to school. The school nurse called asking us what in the world we had done, because she had never seen a case that bad clear up that quickly.

According to Robert O. Young, PhD, author of the bestselling book The pH Miracle, colloidal silver works wonderfully for both eye and ear problems. He states:

“Eye or ear problems, including cataracts, glaucoma, redness, blurred vision, poor eyesight, ringing in the ears, earaches, soreness or swelling of the ears, eardrum damage, hardness of hearing, and (in rare cases) loss of hearing: Use 1 drop of colloidal silver topically (directly in the eye or ear) 3 times a day.”

So Simple to Use – Read These Real-Life Examples!

As you can see, colloidal silver is very simple to use in the eyes. Here are some real-life examples of how people have healed eye infections and other eye issues with colloidal silver:

A colloidal silver user on the Colloidal Silver Success Stories web site says she uses it to help clear up eye allergies and sties:

Relieves Itchy Eyes Due to Allergies

in One Dose; Heals Sties!

I put a drop or two in my eyes 1-3 times a day whenever they feel itchy due to allergies. It’s amazing how fast your eyes feel better, and sometimes all it takes is one dose!

My daughter felt a sty coming on so she put 2 drops of colloidal silver, twice a day in her eye for a couple days, and the sty never developed!

For eye infections due to irritants or a scratched eye, I use 1-2 drops 2 times a day for 2-3 days (longer if needed). The eye will be noticeably better after only 1 treatment!

A colloidal silver user from Canada wrote in, saying:

Healed Boil on Eye and

Stopped Infection in One Day!

I had an eye infection starting. My right eye was red, itchy and had a bit of yellowish discharge. There was a small boil right on the eyelid. So I dunked my eye into some micro-particle colloidal silver water several times over the course of the evening.

The next morning the pus and redness was gone but the boil was still there. So that day I dunked my eye every hour and drank several ounces 3 times. The next day everything was absolutely normal…no redness, no pus, no boil.

And colloidal silver user “Sherry” from Johnson City, TN wrote to say:

Healed Infected Eye


My eye started draining one night, which is very unusual for me. I thought great I’m getting an eye infection.

That night I put 2 drops of colloidal silver in my eye. The next morning my eye was better. I was thrilled and hooked on the benefits of colloidal silver.

  1. Jansen from Scottsdale, AZ wrote to say:

Healed Swollen Face

and Pink Eye in ‘a Couple of Days!’

I’ve also used colloidal silver for a bad case of Pink Eye. It was so bad my whole face was swelling up & my daughter who is an ophthalmologist said I needed to go into the doctor’s office right away.

I just added a couple of drops of the silver into my eye every 30 minutes or so until it was on the mend, which was a couple of days.

Steve C., from Toronto, Canada wrote to say:

Healed Pink Eye Overnight!

I had Pink Eye over a year ago, and I sprayed it right on my eye, perhaps 3 or four times, and my Pink Eye was gone the next morning!

My daughter got it a year later and it worked as easily for her as well. I guess we are just getting used to the everyday miracles this stuff can do!

Another avid colloidal silver user, from Michigan, wrote to say:

Healed Swollen Infected Eye

In Just 20 Minutes!

One morning my 8 year old granddaughter Breanna woke up with her left eye all swollen and full of pus, it was almost totally closed up.

Her mother soaked a wash cloth in the colloidal silver I keep them generously supplied with, made with my Micro-Particle Colloidal Silver Generator.

Breanna held the wash cloth on her eye for 20 minutes, when she removed it the swelling was gone and her eye was all cleared up and the problem did not return.

Our old friend Gramma Bea Riley from Riley Farms in southern California wrote to say:

Heals Eye Infections in

Our Pets and Farm Animals!

Our dog tangled with a bear. Its eye was bloody – we sprayed colloidal silver – within minutes she was prancing around the barn as if nothing had ever happened.

The goat had pink eye – a couple of sprays of colloidal silver took care of it, too.

A reader from Charleston, West Virginia wrote to say:

“No More Blurred Vision”

In the mornings, sometimes there is way too much “gook” in my eyes, and my vision is blurred.

I will clean off the gook and spray one quick spray of colloidal silver into each eye, close them for about ten seconds, blot the dry with a tissue, then there is no more blurred vision.

And a very good friend from southern California wrote to say:

Healed Sticky Yellow Fluid

From Eye in One Day!

I woke up Friday morning with my eyes oozing a sticky yellow fluid. I don’t think I had a cold and my eyes were not pink like they had pink eye. But I had maybe the beginning of it.

I poured colloidal silver from my Micro-Particle Colloidal Silver Generator into a shot glass, put enough pressure on the glass around my eye to seal it, tilted my head back, opened my eye in the silver solution.

Then I did the same with the other eye with fresh colloidal silver.

The yellow fluid was gone and hasn’t come back. Colloidal silver saved me a trip to the Dr.’s and time off from work. I love this stuff!

Ann R.D. from Alabama wrote to say:

Pink Eye Gone In 48 Hours!

I make batches for all family members, all of whom have different purposes for it. For example, our grandson got pink eye. A few drops of silver in each eye had an immediate effect and the pink eye was gone in 48 hours.

I recommended it to a friend whose son’s eyes were swollen shut with pink eye and within 48 hours, his eyes were clear.

Wynona Sue Hill from California wrote to say:

Relieves Eye Discomfort

For Pekinese!

I use it for many things, not the least is to keep my little Pekinese dog healthy. His eyes sometimes bother him. I keep spray bottles handy and use it. It immediately relieves his discomfort.

Jan, from Northglenn, Colorado writes to say:

Relieves Itchy Eyes Fast!

I have several favorite ways to use silver from my Micro-Particle Colloidal Generator – I usually drink an ounce daily which helps keep me pretty healthy.

BUT sometimes, my eyes will itch with a potential eye infection which can be a very serious problem. So out comes a liqueur glass into which I pour some silver for an eye wash and the itching soon disappears.

And a Registered Nurse from Highland, Utah wrote to say:

Nurse Cures Own

Eye Infections!

I’m an RN with a BSN from a large university. My father is a retired dentist. We are a medical family. So the biggest hurdle for me was to let myself experiment with colloidal silver and give it a chance.

My father had begun researching ‘silver’ and using it a few years ago. At the same time I was experiencing repeated eye infections. I grew tired of paying for doctor visits and medication, and used the ‘silver’ (as my family and I call it). And I found I could cure the infections myself.

A 78-year old lady from Michigan wrote with an astonishing story about avoiding cornea transplants thanks to her daily colloidal silver usage:

Eyesight Improving at 78 Years Old!

I drink about 2-oz portions per day…Another wonderful and unexpected bonus I attribute to these four years of colloidal silver treatments is that my eyes have improved greatly over that period. My eye specialist had been preparing me for blindness with some help possible with cornea transplants.

Colloidal silver user Christina M., wrote to say:

Pink Eye Cured in Several Days!

Months ago my son-in-law-to-be had pink eye so I told him to purchase some CS and put it in his eye. He was amazed that it was completely gone in about 3 days.

He recently got Pink Eye again so I gave him some of my home brewed colloidal silver and he said in minutes the irritated feeling was gone and by the end of the second day after using it only twice per day the Pink Eye was completely gone.

Dale W., wrote to explain how he used colloidal silver to eliminate eye infections in his family’s kittens:

Healed Kittens With Infected Eyes!

One of the uses that we use colloidal silver for is on our cats. We have outside cats that have never seen a vet. Before colloidal silver was being used their health was marginal.

Kittens in the past would have these serious eye infections shortly after birth, but by using colloidal silver spray on the 2 most recent litters of kittens the infections were under control on the 1st group (they were born just before we got our generator) and the second, most recent litter, there were no infections at all.

We started spraying their eyes about 2 weeks after birth. BTW — the females are spayed now—no more litters—-but we use colloidal silver in all of the cat’s food (about a tbsp. per bowl) twice a day. They are looking great!!!!!

Jenn F. wrote to say:

Healed Infected Eye

In Just One Day!

My step son flew out for a visit in the summer, and when he got off the plane his eye was so infected that he couldn’t open it…

…I immediately put silver drops into his eye, and by morning it was fine.

And finally, Sheila S. wrote to explain how she cured her horse’s bad case of moon blindness with colloidal silver:

Healed “Moon Blindness” in Horse

My list of uses for colloidal silver are long. I started reading about colloidal silver when my horse acquired moon blindness. The vet said there was no cure and she would probably eventually lose both eyes. I couldn’t accept it so I went looking for a cure.

I suspected the mare had some auto immune issues and I read the people had used colloidal silver for this. I first purchased colloidal silver from an individual that made it. The eye went from being blue and nasty (she couldn’t see out of it) to eventually becoming clear.

We used colloidal silver off and on for about a year and a half. We haven’t given her any for over a year and a half and you would never know that she ever had had issues with moon blindness!

(All of these testimonials are from real people, and they can be found along with dozens and dozens of others at the Colloidal Silver Success Storiesweb site.)

Powerfully Effective

As you can see, colloidal silver is simple to use in the eyes, and is powerfully effective.

Only a few drops in the affected eye, as many as three times a day, and eye infections seem to be resolved almost overnight!

What About Cataracts?

Here’s an interesting discourse between myself and a member of the Colloidal Silver Secrets Community on Facebook, regarding colloidal silver and cataracts:

Group Member: “Interesting thing, I had a retinal detachment in May of this year and had surgery. My surgeon said that I would probably develop cataracts in that eye and need cataract surgery.

Unfortunately, I started to develop a small cataract which was getting increasingly bothersome. I knew he would recommend surgery when I go to see him again this spring.

However, since I began taking the silver orally, I believe my cataract may be clearing up. So I googled ‘colloidal silver and cataract’ and came up, yet again, to your website! I am blown away and had no idea that colloidal silver could clear cataracts.

I have been praying to avoid another eye surgery. And since my eye surgery, I am terrified to put anything directly into my eye, even silver (although I have done it in the past, before the surgery).

Do you think if I continue to take colloidal silver orally that it will have enough power to clear my cataract totally? Many thanks!”

Steve: To be completely frank with you, Jessica, the information on our web site about colloidal silver and cataracts is a quote from Dr. Robert O. Young’s bestselling book, The pH Miracle,” and it is the only place in the world I’ve seen that recommends using colloidal silver for cataracts.

Dr. Young does not explain the mechanism through which he believes colloidal silver could help cataracts. I personally don’t understand his reasoning, unless he believes there is an underlying infection of the eye that allows cataracts to form.

In such a case, the silver would destroy the infectious agent, and then I suppose the cataract formation would stop.

But…I’ve seen no clinical studies to justify this supposition. So, I’m not disagreeing with Dr. Young. I’m just still trying to find a “second witness,” so to speak, to his contentions.

There are lots of anecdotes on the internet offering supportive information to the contention that colloidal silver can be helpful against cataract development, including this one in which a dog was supposedly cured of cataracts.

Group Member (a week later): “Well, I don’t know how it works either, but it apparently does, because my cataract is now almost completely gone.

Granted, it was small to begin with, but it was growing and becoming increasingly annoying.

I only detect a very… small piece of it when I close my eyes now…of course, I will have to see what my doc says in the spring, but I am hoping that my daily dose will keep whatever was developing there at bay.”

The Bottom Line

The bottom line is that thousands of people use colloidal silver successfully in their eyes, with amazing results.

Some say it cures their eye infections, such as Pink Eye infections and sties (staph infections of the eyes).

Others say it helps them with allergies, itchy eyes, morning eye “crust,” and other similar problems.

Some even say it helps them with more serious eye problems, like cataracts.

Of course, my position is that when it comes to your eyes, you should always tell you doctor what you’re doing so he can monitor your situation carefully. That way, you’ll know for sure if colloidal silver is helping, or not.

And of course, never overdo it. As you can see from the above real-life accounts, there are a number of ways to use colloidal silver in the eyes:

  • Most people simply put a few drops into their eyes at a time.
  • Others used a pump spray bottle with a fine mist to lightly spray a bit of colloidal silver into their eyes.
  • Some used colloidal silver in a shot glass as an eye wash.
  • And some soaked a cloth in colloidal silver and simply held it over their eye, for excellent results.

Silver is very powerful, and in the eyes, a little bit appears to go a long way.

Helpful Links:

Video: Learn How to Make Micro-Particle Colloidal Silver

.999 Fine Pure Silver Wire for Making Colloidal Silver

Get Your FREE Colloidal Silver “Safe Dosage” Report

Join the Colloidal Silver Secrets Community on Facebook

The New Micro-Particle Colloidal Silver Generator

Subscribe to the Colloidal Silver Secrets Ezine

Make Your Own Colloidal Silver Inexpensively

Real-Life Colloidal Silver Success Stories

Colloidal Silver Update (News & Views)

The Ultimate Colloidal Silver Manual

The Colloidal Silver Secrets Video

Colloidal Silver Kills Viruses

Colloidal Silver Cures MRSA

Colloidal Silver Secrets blog

Meet Steve Barwick

Flea and tick powder DIY

How To Make An Effective Flea And Tick Powder For Your Pets

How  To Make An Effective Flea And Tick Powder For Your Pets

Nobody likes to see their pets bothered by fleas and ticks. Here is a recipe using four ingredients that can be used on your four legged friends as well as in the garden for repelling and killing fleas, ticks, mosquitos, ants, spiders and other bugs and is recommended by holistic vets.

Contrary to popular belief fleas cannot fly, but are passed from pet to pet contact, or from furnishings or even plants onto pets. Their bites start a nasty cycle of itching and scratching. In severe cases it can result in hair loss, skin inflammation or infection to your beloved furry friends. Some chemical solutions will cause allergic reactions and also resistance can be built up over time hence rendering them less effective.

This homemade remedy uses four ingredients that are recognized as insect repellents. Here is a brief description of each:

Eucalyptus (eucalyptus globulus, eucalyptus citriodoro) is a known natural bug and insect repellent. Eucalytpus oil is an effective way to get rid of fleas in your home. It comes from the seeds of the eucalyptus tree and produces a strong scent that fleas and other insects find unbearable. Studies have shown that it can be more effective than DEET. An additional benefit of this essential oil is that it is an antiseptic so can sooth the skin following insect bites.

(Please note this ingredient should be omitted if applying to cats as they are sensitive to many essential oils. Eucalyptus oil should not be ingested by pets. Do not allow your pet to chew on toys, collars or bedding that is treated directly with the oil).

Yarrow is a healing herb which can be used to treat wounds due to it’s anti-inflammatory properties and used to be a vital herb used in wartime. It has also been shown to have pain relieving properties and is anti-microbial. Pets that suffer from a flea infestation will often go on to get infected bites. Powdered yarrow can help heal and sooth the irritated skin helping to stop the itching/scratching vicious circle.

Neem is another herb which has been used for centuries due to it’s antiseptic, anti-bacterial, anti-fungal, anti-viral, and blood-purifying properties. It can be used on pets in oil or powder form as a herbal insect repellent, repelling fleas, ticks, lice, mites, ants and mosquitoes (i) . It actually inhibits the metamorphosis of the larvae thus preventing the rapid breeding of these bugs. It is also moisturising so it helps heal any dry skin or scaling which would otherwise occur from the skin irritation.

This is also known as Diatomaceous Earth (DE) and is a naturally occurring, soft, siliceous sedimentary rock consisting of fossilized remains of diatoms, a type of hard-shelled algae, that is easily crumbled into a fine white to off-white powder. DE particles are so small so it just feels like a fine baby powder to humans and pets. It is a simply a mineral silica.
Food grade fresh water DE is harmless to humans and pets because it is not a poison – the bugs do not ingest it. DE is chrystaline in structure. It works by scratching the bodies of the insects and causing them to dehydrate. Because Diatomaceous Earth can by very drying, Neem counteracts the dryness and helps protect your pet from excess dry skin.
This food grade DE can be purchased at some plant nurseries BUT be sure and specify that you want food grade (not crystallized or filter grade). DE products are registered for use against bed bugs, cockroaches, crickets, fleas, ticks, spiders, and many other pests.

20 drops of Eucalyptus Essential Oil (remember to omit this for cats)
Half a cup of Yarrow Powder
Half a cup of Neem Powder
1 cup of Food Grade Diatomaceous Earth

Simply mix all of the above together in a jar with a shaker lid. Sprinkle on to your pet along the spine whilst brushing the fur in the opposite direction to ensure the powder makes contact with the skin. Also rub it onto their belly, legs and tail always ensuring that it gets to the skin. It can help to rub in with a powder puff or cotton wool pad. Take care to avoid any contact with their eyes and nose.

When this is being applied as a preventative measure once a month should keep your pet bug free throughout the spring and summer months when fleas are most prevalent. However following a bath or they go out in the wet then you should reapply.
If it is being applied to treat an active infestation then apply every other day until you can no longer see any trace of the fleas. Then just apply as above for maintenance.
It is important to also treat your home to prevent re-infestation. You can apply this same powder to pet bedding, soft furnishings, windowsills and floors. Just apply a light dusting to these areas and leave it overnight. Vacuum the following day. Repeat once a week for a month.

For other natural ways to effectively get rid of fleas from your home, garden and pets please see :

(i) http://www.discoverneem.com/neem-oil-for-dogs.html

If you know a pet owner who would love to banish fleas and ticks without resorting to harsh chemicals then please feel free to share this information by clicking one of the share buttons below.

Bovine, chicken and human components in vaccines?!!!!!!!

3 easy steps to decide …….

Just like reading a label on products purchased at the grocery store, parents should read and understand what a pediatrician could be injecting into their child – beforethey vaccinate them. Often times parents are discouraged from looking deeper into the matter because some pediatricians act like playground bullies more than doctors. Below are 3 easy steps for any new parent to start their own investigation and form their own opinion on vaccines.


Just like reading a label on products purchased at the grocery store, parents should read and understand what a pediatrician could be injecting into their child – beforethey vaccinate them. Often times parents are discouraged from looking deeper into the matter because some pediatricians act like playground bullies more than doctors. Below are 3 easy steps for any new parent to start their own investigation and form their own opinion on vaccines.

Step 1 – What is in This Vaccine?

New parents can find a summary of ingredients from official government sources. The Centers for Disease Control has a ‘Fact Sheet’ on vaccine ingredients (http://www.cdc.gov/vaccines/vac-gen/additives.htm). Two links are available on this page for additional information:

For example, if a parent wanted to know the ingredients (excipients) of the MMR vaccine, they would look at the Vaccine ingredients sorted by vaccine PDF. Below is a  buffet of ingredients the parent would discover in the MMR vaccine, and that’s just the beginning.

Amino Acid, Bovine Albumin or Serum, Chick Embryo Fibroblasts, Human Serum Albumin, Gelatin, Glutamate, Neomycin, Phosphate Buffers, Sorbitol, Sucrose, Vitamins

Please remember this point: the CDC links are a good starting point, but parents often require more information. The information parents need is located on what is called the vaccine insert. Sticking with the MMR vaccine example, the vaccine insert for the MMR-II vaccine can be found online.(http://www.merck.com/product/usa…) (pdf)

Reading the vaccine insert reveals not only the ingredients, but also the fact the vaccine has not been tested for carcinogenesis (cancer causing), mutagenesis (DNA changing) or impairment of fertility. We’re not done yet.

Parents should also be interested in the “ADVERSE REACTIONS” and “CONTRAINDICATIONS” sections of the document. A contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment. Many pediatricians do not test for contraindications prior to vaccinating babies.

If parents don’t understand the technical medical jargon, that’s okay. Resources like the Merck Manual (http://www.merckmanuals.com/home/index.html) can help decipher some of the medical code.

*** Vactruth.com has a list of all of the vaccine inserts. Find them here(http://vactruth.com/vaccine-inserts/) or scroll to the bottom of the website and look under the hyperlink “Vaccine Inserts”. Parents may want to see how old their child is to determine what vaccine to look at first. The CDC vaccine schedule(http://www.cdc.gov/vaccines…) (pdf) will show the parent what vaccines are recommended for a specific age.


Step 2 – What Are These Ingredients Anyways?

You think I’m exaggerating, don’t you? Read on.

Each chemical in the vaccine has a “social security number”. The specific name for the chemical number is called a CAS (Chemical Abstracts Service) number. Humbolt State University Library describes CAS numbers like this,

Chemical Abstracts Service (CAS) has a registry system for all completely identified chemical compounds or substances. There are over 113 million chemical substances & sequences currently registered … Each individual chemical substance is assigned a CAS Registry Number which may be thought of as that substance’s “Social Security number.”(http://library.humboldt.edu…)

Once a parent has the CAS number for a chemical in the vaccine, they can look up the chemical with precision. Where would the CAS number be useful? Parents could type in the CAS number or the chemical name on a number of helpful sites.

  • Pubchem (http://pubchem.ncbi.nlm.nih.gov/)
    Free database of chemical structures of small organic molecules and information on their biological activities
  • TOXNET (http://toxnet.nlm.nih.gov/)
    Databases on toxicology, hazardous chemicals, environmental health, and toxic releases.
  • MSDS (http://www.msds.com/)
    Access to the widest selection of material safety data sheets (“MSDS”) to a large group of people.


Step 3 – What Could This Vaccine Do to My Baby?

I saved the best for last. The Vaccine Adverse Event Reporting System (VAERS)(http://www.medalerts.org/vaersdb/index.php) will show the parent researcher adverse reactions reported by parents and physicians on specific vaccines. VAERS is a passive system which means there could be many more adverse events to vaccines that go unreported.

I’ve never been more serious than right now. Parents can blindly trust their pediatrician’s word that vaccines are safe and ignore this advice at their own peril. Or, parents can start to investigate vaccines for themselves and form their own opinions about the safety of the chemicals in vaccines.

* * *

Did you find the resources mentioned in this article helpful? What other resources could be used to help new parents? What helped you decide to vaccinate or not vaccinate your child?


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